Bleeding with ipi/nivo

Forums General Melanoma Community Bleeding with ipi/nivo

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    sks2019
    Participant
      My mom is on the ipi/nivo combo for her liver Mets,she was diagnosed last year with vaginal melanoma. Started on opdivo in feb 2019 , May 2019 her scans were good with no tumor only inflamed lymph nodes and August 2 liver Mets . she’s due for her 3 infusion next week. She is now getting vaginal spotting like we would see with menstrual cycles. It turned from dark brown to red ( sorry for the description) . I am scared is this a new tumor somewhere now ? Has anyone seen or experienced anything like this before ? Could it be any hormonal issues ? My mom is 59 and menopaused like 10 years ago.
      Has anyone seen bleeding if the combo is working?
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        sks2019
        Participant
          Just in case someone here is looking for the same side effects and For the sake of rarity of the side effects my mom is experiencing I am replying to my own post. I just spoke to the nurse regrading her bleeding iissue and blood in the urine confirmed with Urine analysis.
          He said the nurses talked to each other and one of the nurse mentioned that she had previously seen a patient with vaginal melanoma experiencing bleeding with the Immunotherapy and they will treat it as a side effect. He also suggested to see a gynecologist so that a gyne can take a look inside to see if there is anything to be of concern. My mom;s last scan in Aug were good atleast for the vaginal area.
          Still praying this is not a new met. God bless all !
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