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I have only been on Zelboraf for about 6 weeks, but so far so good. Side effects have been very mild and only recently noticable (about 2 weeks). Some fatigue that has been NOTHING like the fatigue I felt from the year of Interferon. And some slight soreness in either wrist but not both at same time.   After first 28 day cycle had great decrease in liver enzymes and a significant amount of tumor shrinkage in several visible tumors, with no new tumor evidence. Feeling great and very positive.

Hope this helps and best wishes

I have only been on Zelboraf for about 6 weeks, but so far so good. Side effects have been very mild and only recently noticable (about 2 weeks). Some fatigue that has been NOTHING like the fatigue I felt from the year of Interferon. And some slight soreness in either wrist but not both at same time.   After first 28 day cycle had great decrease in liver enzymes and a significant amount of tumor shrinkage in several visible tumors, with no new tumor evidence. Feeling great and very positive.

Hope this helps and best wishes

I started Zelboraf 8/2/11 as part of clinical trial. 2 weeks into initial month, drug approved by FDA. Currently on 2nd 28 day cycle of treatment under trial umbrella. Will continue treatment without benefit of trial.

So far, looking good. Major improvements in liver enzymes and tumor shrinkage of several tumors noted after first 28 day cycle. Had no side effects during first cycle. Starting to experience some fatigue during the second cycle, however this fatigue is nothing compared to fatigue from interferon. Also notices variable discomfort in wrists some days.

Next series of scans scheduled after third cycle. Hopeful that scans will show significant improvement through-out.

I started Zelboraf 8/2/11 as part of clinical trial. 2 weeks into initial month, drug approved by FDA. Currently on 2nd 28 day cycle of treatment under trial umbrella. Will continue treatment without benefit of trial.

So far, looking good. Major improvements in liver enzymes and tumor shrinkage of several tumors noted after first 28 day cycle. Had no side effects during first cycle. Starting to experience some fatigue during the second cycle, however this fatigue is nothing compared to fatigue from interferon. Also notices variable discomfort in wrists some days.

Next series of scans scheduled after third cycle. Hopeful that scans will show significant improvement through-out.