Good morning, so sorry to hear about your wife. I would consider contacting someone in the melanoma department at Sloane Kettering. Without contacting them and getting the best and latest information, I don't think my husband would be a 1 + year survivor today.
Questions we have learned to ask is the depth of the cancer, of course stage, what treatment options are available, clinical trials (check with NIH), type of melanoma.
Do some research on the latest drugs available as well and don't be afraid to contact the drug companies directly as they have information that you won't find anywhere else.
The best advice I can give you is DON'T GIVE UP, be aggressive and question everything.
Best to you and your wife.
