laheasley

Dermatopathology Report

Diagnosis:

Malignant melanoma

Breslow's Thickness – 0.46mm

Clark's Level – III

Ulceration – Absent

Regression – Not Observed

Mitotic Rate – zero per square mm

Host Lymphocytic Response – Non-brisk

Associated Lesion – Possible small vestige of intradermal nevus (172.5)

Clinical Information:

Clinical History:  atypical

Specimen Data:

Specimen Type/Location:  Breast, Left

Gross Description: Received in formalin is an irregular piece of skin measuring 0.8 cm in greatest dimension.  The specimen is entirely submitted.

Microscopic Examination:  Sections demonstrate skin with a confluent atypical melanocytic proliferation at the dermal-epidermal junction, composed as irregular nests and single units.  Some areas display confluent single cell growth.  The cells are intermediate to large in size with abundant dusty amphophilic cytoplasm and nuclear atypia characterized by hyperchromasia, pleomorphism and conspicuous nucleoli.  There is marked pagetoid extension of single cells and small dyscohesive nests.  Exceptionally rare mitotic figures are present.  The process extends into and focally fills the papillary dermis to a depth of 0.46 mm.  There is a very small focus in the dermal component where the cells tend to nest more, display much less atypica and mild changes of maturation.  Elsewhere, the deepest components display cytoplasmic evidence of melanogenesiis and minimal maturation.

I am scheduled to have a Wide Local Excision at 8 a.m. in the morning.  I was not too worried when I initially got the news, but as it gets closer, I am starting to have bad/worrisome feelings.  I have the report but I don't understand what any of it means.  I think it looks pretty good – at least the parts I can figure out!  But there are parts that concern me … specifically "possible small vestige of intradermal nevus" and basically the whole paragraph after "microscopic examination" …

Any advice???

Dermatopathology Report

Diagnosis:

Malignant melanoma

Breslow's Thickness – 0.46mm

Clark's Level – III

Ulceration – Absent

Regression – Not Observed

Mitotic Rate – zero per square mm

Host Lymphocytic Response – Non-brisk

Associated Lesion – Possible small vestige of intradermal nevus (172.5)

Clinical Information:

Clinical History:  atypical

Specimen Data:

Specimen Type/Location:  Breast, Left

Gross Description: Received in formalin is an irregular piece of skin measuring 0.8 cm in greatest dimension.  The specimen is entirely submitted.

Microscopic Examination:  Sections demonstrate skin with a confluent atypical melanocytic proliferation at the dermal-epidermal junction, composed as irregular nests and single units.  Some areas display confluent single cell growth.  The cells are intermediate to large in size with abundant dusty amphophilic cytoplasm and nuclear atypia characterized by hyperchromasia, pleomorphism and conspicuous nucleoli.  There is marked pagetoid extension of single cells and small dyscohesive nests.  Exceptionally rare mitotic figures are present.  The process extends into and focally fills the papillary dermis to a depth of 0.46 mm.  There is a very small focus in the dermal component where the cells tend to nest more, display much less atypica and mild changes of maturation.  Elsewhere, the deepest components display cytoplasmic evidence of melanogenesiis and minimal maturation.

I am scheduled to have a Wide Local Excision at 8 a.m. in the morning.  I was not too worried when I initially got the news, but as it gets closer, I am starting to have bad/worrisome feelings.  I have the report but I don't understand what any of it means.  I think it looks pretty good – at least the parts I can figure out!  But there are parts that concern me … specifically "possible small vestige of intradermal nevus" and basically the whole paragraph after "microscopic examination" …

Any advice???

Dermatopathology Report

Diagnosis:

Malignant melanoma

Breslow's Thickness – 0.46mm

Clark's Level – III

Ulceration – Absent

Regression – Not Observed

Mitotic Rate – zero per square mm

Host Lymphocytic Response – Non-brisk

Associated Lesion – Possible small vestige of intradermal nevus (172.5)

Clinical Information:

Clinical History:  atypical

Specimen Data:

Specimen Type/Location:  Breast, Left

Gross Description: Received in formalin is an irregular piece of skin measuring 0.8 cm in greatest dimension.  The specimen is entirely submitted.

Microscopic Examination:  Sections demonstrate skin with a confluent atypical melanocytic proliferation at the dermal-epidermal junction, composed as irregular nests and single units.  Some areas display confluent single cell growth.  The cells are intermediate to large in size with abundant dusty amphophilic cytoplasm and nuclear atypia characterized by hyperchromasia, pleomorphism and conspicuous nucleoli.  There is marked pagetoid extension of single cells and small dyscohesive nests.  Exceptionally rare mitotic figures are present.  The process extends into and focally fills the papillary dermis to a depth of 0.46 mm.  There is a very small focus in the dermal component where the cells tend to nest more, display much less atypica and mild changes of maturation.  Elsewhere, the deepest components display cytoplasmic evidence of melanogenesiis and minimal maturation.

I am scheduled to have a Wide Local Excision at 8 a.m. in the morning.  I was not too worried when I initially got the news, but as it gets closer, I am starting to have bad/worrisome feelings.  I have the report but I don't understand what any of it means.  I think it looks pretty good – at least the parts I can figure out!  But there are parts that concern me … specifically "possible small vestige of intradermal nevus" and basically the whole paragraph after "microscopic examination" …

Any advice???