bllowe

Hi, just found this site & noticed that there was some discussion re: Temodar.  My husband, Bobby (73) has stage 4 Melanoma.  He had a superficial spreading mel in 1996 (excised – no further treatment).  We had almost forgotten about it until Jan 2010 when it appeared in his right axilla (surgery & radiation).  October 2010 had spread to right lung.

Of the few options available, we chose Tamodar (390mg at bedtime) with Zofran taken 30 min. before dosing.  He slept well & woke up in the mornings feeling fine..  No side effects at all except a little constipation.  It was great!  Worked fast to shrink tumors.  Held them at bay for over a year.

In March 2012 Lung tumors were growing & an MRI @ MDA Houston showed 2 brain lesions.  Soooo…he was no longer a candidate for planned lung surgery.  The Brain tumors were zapped with a gamma knife, and that went fine.

Bobby started Zelboraf 960mg 2x daily.  By day 12 he had a terrible rash from the top of his head to his knees, and had to suspend the Zelboraf.  He's been off for 3 days & is treating the rash – better, but isn't to start back till rash is mostly gone.  His dermatologist is saying start back with 1 tablet 2x daily & slowly build back up.  His oncologist is saying start back with 3 tabs 2x daily & see if rash comes back.

QUESTION:  What have others experienced with reinduction of the Zelboraf?

Hi, just found this site & noticed that there was some discussion re: Temodar.  My husband, Bobby (73) has stage 4 Melanoma.  He had a superficial spreading mel in 1996 (excised – no further treatment).  We had almost forgotten about it until Jan 2010 when it appeared in his right axilla (surgery & radiation).  October 2010 had spread to right lung.

Of the few options available, we chose Tamodar (390mg at bedtime) with Zofran taken 30 min. before dosing.  He slept well & woke up in the mornings feeling fine..  No side effects at all except a little constipation.  It was great!  Worked fast to shrink tumors.  Held them at bay for over a year.

In March 2012 Lung tumors were growing & an MRI @ MDA Houston showed 2 brain lesions.  Soooo…he was no longer a candidate for planned lung surgery.  The Brain tumors were zapped with a gamma knife, and that went fine.

Bobby started Zelboraf 960mg 2x daily.  By day 12 he had a terrible rash from the top of his head to his knees, and had to suspend the Zelboraf.  He's been off for 3 days & is treating the rash – better, but isn't to start back till rash is mostly gone.  His dermatologist is saying start back with 1 tablet 2x daily & slowly build back up.  His oncologist is saying start back with 3 tabs 2x daily & see if rash comes back.

QUESTION:  What have others experienced with reinduction of the Zelboraf?

Hi, just found this site & noticed that there was some discussion re: Temodar.  My husband, Bobby (73) has stage 4 Melanoma.  He had a superficial spreading mel in 1996 (excised – no further treatment).  We had almost forgotten about it until Jan 2010 when it appeared in his right axilla (surgery & radiation).  October 2010 had spread to right lung.

Of the few options available, we chose Tamodar (390mg at bedtime) with Zofran taken 30 min. before dosing.  He slept well & woke up in the mornings feeling fine..  No side effects at all except a little constipation.  It was great!  Worked fast to shrink tumors.  Held them at bay for over a year.

In March 2012 Lung tumors were growing & an MRI @ MDA Houston showed 2 brain lesions.  Soooo…he was no longer a candidate for planned lung surgery.  The Brain tumors were zapped with a gamma knife, and that went fine.

Bobby started Zelboraf 960mg 2x daily.  By day 12 he had a terrible rash from the top of his head to his knees, and had to suspend the Zelboraf.  He's been off for 3 days & is treating the rash – better, but isn't to start back till rash is mostly gone.  His dermatologist is saying start back with 1 tablet 2x daily & slowly build back up.  His oncologist is saying start back with 3 tabs 2x daily & see if rash comes back.

QUESTION:  What have others experienced with reinduction of the Zelboraf?