Aussie Cookie

I had a really bad reaction the the taf/mek combi when I went on it for the second time after pd1 treatment. I started really low doses and worked my way up to 5 days on 2 days off. It took about 8 months to get to that stage. I was stable for 16months. Good luck to your husband. They also have 50mg taf tablets which might be easier to tolerate.

I had a really bad reaction the the taf/mek combi when I went on it for the second time after pd1 treatment. I started really low doses and worked my way up to 5 days on 2 days off. It took about 8 months to get to that stage. I was stable for 16months. Good luck to your husband. They also have 50mg taf tablets which might be easier to tolerate.

I had a really bad reaction the the taf/mek combi when I went on it for the second time after pd1 treatment. I started really low doses and worked my way up to 5 days on 2 days off. It took about 8 months to get to that stage. I was stable for 16months. Good luck to your husband. They also have 50mg taf tablets which might be easier to tolerate.

Hi rebekah

this time last year I went through the worst joint pain and swelling in my knees that I've ever experienced. It came off the back of being on pd1 for 6 months with progression to going straight back onto braf mek. I had been on the combi before with only minor fever. What hit me this time was very unexpected. My knees were so swollen I couldn't bend them. I also ended up on prednisone in the end it took the last twelve months to become stable on these drugs again.  At the beginning we cut back my dose to once a week. Over the last year we've built up to 5days on and two days off. This seems to be a working combination for me. I'm off the prednisone and the anti inflammatories. My disease is still stable so that's a good thing too. I hope your husband is on the mend soon. The anti inflammatories and prednisone really helped me.

Hi rebekah

this time last year I went through the worst joint pain and swelling in my knees that I've ever experienced. It came off the back of being on pd1 for 6 months with progression to going straight back onto braf mek. I had been on the combi before with only minor fever. What hit me this time was very unexpected. My knees were so swollen I couldn't bend them. I also ended up on prednisone in the end it took the last twelve months to become stable on these drugs again.  At the beginning we cut back my dose to once a week. Over the last year we've built up to 5days on and two days off. This seems to be a working combination for me. I'm off the prednisone and the anti inflammatories. My disease is still stable so that's a good thing too. I hope your husband is on the mend soon. The anti inflammatories and prednisone really helped me.

Hi rebekah

this time last year I went through the worst joint pain and swelling in my knees that I've ever experienced. It came off the back of being on pd1 for 6 months with progression to going straight back onto braf mek. I had been on the combi before with only minor fever. What hit me this time was very unexpected. My knees were so swollen I couldn't bend them. I also ended up on prednisone in the end it took the last twelve months to become stable on these drugs again.  At the beginning we cut back my dose to once a week. Over the last year we've built up to 5days on and two days off. This seems to be a working combination for me. I'm off the prednisone and the anti inflammatories. My disease is still stable so that's a good thing too. I hope your husband is on the mend soon. The anti inflammatories and prednisone really helped me.