› Forums › General Melanoma Community › Zelboraf Regression and a Plan B
- This topic has 3 replies, 1 voice, and was last updated 13 years, 7 months ago by
FormerCaregiver.
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- June 27, 2012 at 9:10 pm
Hi Everyone:
My dad starting taking Zelboraf at the standard dose on March 19, 2012, his Melanoma was quite advanced.. He was a responder to the treatment with tumour reduction in lungs, spleen, spine. In May he started to get external regrowth on his neck. Will get the neck growth radiated. Waiting to get his CT scan results back this week. Speculating that it will likely show tumour growth and regression.
Hi Everyone:
My dad starting taking Zelboraf at the standard dose on March 19, 2012, his Melanoma was quite advanced.. He was a responder to the treatment with tumour reduction in lungs, spleen, spine. In May he started to get external regrowth on his neck. Will get the neck growth radiated. Waiting to get his CT scan results back this week. Speculating that it will likely show tumour growth and regression.
I know lots of people are in the same boat in terms of running into the resistance issue. Just hoping to hear some ideas in terms of a Plan B of attack.
MRF is the place I keep coming back to for snippets of hope.
Thanks,
Adrian
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- June 29, 2012 at 5:22 am
Adrian, welcome to our forum. I encourage you to fill in some info on the profile page
that you may wish to create for your dad. This will help us to help you better.Zelboraf can be very effective in some cases. However, other drugs such as MEK/PI3K or
HSP90 inhibitors (XL888) should ideally be included in the treatment plan. (See:
http://clincancerres.aacrjournals.org/content/early/2012/02/18/1078-0432.CCR-11-2612).Hope this helps
Frank from Australia
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- June 29, 2012 at 5:22 am
Adrian, welcome to our forum. I encourage you to fill in some info on the profile page
that you may wish to create for your dad. This will help us to help you better.Zelboraf can be very effective in some cases. However, other drugs such as MEK/PI3K or
HSP90 inhibitors (XL888) should ideally be included in the treatment plan. (See:
http://clincancerres.aacrjournals.org/content/early/2012/02/18/1078-0432.CCR-11-2612).Hope this helps
Frank from Australia
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- June 29, 2012 at 5:22 am
Adrian, welcome to our forum. I encourage you to fill in some info on the profile page
that you may wish to create for your dad. This will help us to help you better.Zelboraf can be very effective in some cases. However, other drugs such as MEK/PI3K or
HSP90 inhibitors (XL888) should ideally be included in the treatment plan. (See:
http://clincancerres.aacrjournals.org/content/early/2012/02/18/1078-0432.CCR-11-2612).Hope this helps
Frank from Australia
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