Zelboraf it is.

Forums General Melanoma Community Zelboraf it is.

  • Post
    himynameiskevin
    Participant

      Well it turns out because of the recent brain mets and steroids, I don't qualify for any trials I was hoping for right now. The news was a little disappointing, but kind of expected and completely understandable. I know that if Zelboraf does work for me, it's only a temporary solution, which makes me a little nervous, but I remind myself a temporary solution is better than no solution, and if all works out, maybe it'll get me to a point of stability where I could qualify for a trial of some kind down the line.

      Well it turns out because of the recent brain mets and steroids, I don't qualify for any trials I was hoping for right now. The news was a little disappointing, but kind of expected and completely understandable. I know that if Zelboraf does work for me, it's only a temporary solution, which makes me a little nervous, but I remind myself a temporary solution is better than no solution, and if all works out, maybe it'll get me to a point of stability where I could qualify for a trial of some kind down the line. I'll be seeing a doctor on Wednesday and hopefully get started on Zelboraf as soon as possible. I also have another brain MRI Monday morning to assess what might be a possible lesion or two, but might just be blood vessels. I'd be ok with either, just praying that nothing new shows up. I'm a little anxious and a little nervous at the moment, having the weekend of waiting in front of me. But I'm hanging in there and know these feelings will pass, as they have before, just have to stay focused, and remember all the things to be thankful and hopeful for. Thanks for hearing me out.

      As always, I'm thinking and hoping for the best, for all of us.
      -Kevin

    Viewing 23 reply threads
    • Replies
        WendyPam
        Participant

          Hi Kevin,

          Zeloraf doesn't have to be considered temporary. If you go on MIF a gentlemen Dick has been on it 2 years! (dick_k)  Kevin I am sending you great positive vibes. Others have had wonderful results with Zelboraf for over 6+ months and still going strong…

          My Mom is Stage 4 doing a reinduction of Yervoy,…….

           

          Wendy

            Richard_K
            Participant

              I also post on this forum under Dick_K and my profile is current.

              Dick

              Richard_K
              Participant

                I also post on this forum under Dick_K and my profile is current.

                Dick

                Richard_K
                Participant

                  I also post on this forum under Dick_K and my profile is current.

                  Dick

                WendyPam
                Participant

                  Hi Kevin,

                  Zeloraf doesn't have to be considered temporary. If you go on MIF a gentlemen Dick has been on it 2 years! (dick_k)  Kevin I am sending you great positive vibes. Others have had wonderful results with Zelboraf for over 6+ months and still going strong…

                  My Mom is Stage 4 doing a reinduction of Yervoy,…….

                   

                  Wendy

                  WendyPam
                  Participant

                    Hi Kevin,

                    Zeloraf doesn't have to be considered temporary. If you go on MIF a gentlemen Dick has been on it 2 years! (dick_k)  Kevin I am sending you great positive vibes. Others have had wonderful results with Zelboraf for over 6+ months and still going strong…

                    My Mom is Stage 4 doing a reinduction of Yervoy,…….

                     

                    Wendy

                    aldakota22
                    Participant

                      Hang in there . Zelboraf has shown to work and is working longer on average more than 2x than thought.Time is both our freind and enemy.Praying it all works out for you.

                      aldakota22
                      Participant

                        Hang in there . Zelboraf has shown to work and is working longer on average more than 2x than thought.Time is both our freind and enemy.Praying it all works out for you.

                        aldakota22
                        Participant

                          Hang in there . Zelboraf has shown to work and is working longer on average more than 2x than thought.Time is both our freind and enemy.Praying it all works out for you.

                          scots
                          Participant
                            Keep that positive attitude . I will be praying for you.
                            Scot
                            scots
                            Participant
                              Keep that positive attitude . I will be praying for you.
                              Scot
                              scots
                              Participant
                                Keep that positive attitude . I will be praying for you.
                                Scot
                                Lori C
                                Participant

                                  That sounds like a good plan, Kevin.  You have been and will continue to be in my thoughts & prayers.  You are fighting this with courage and great spirit. 

                                   

                                  Lori, caregiver to Will

                                  Lori C
                                  Participant

                                    That sounds like a good plan, Kevin.  You have been and will continue to be in my thoughts & prayers.  You are fighting this with courage and great spirit. 

                                     

                                    Lori, caregiver to Will

                                    Lori C
                                    Participant

                                      That sounds like a good plan, Kevin.  You have been and will continue to be in my thoughts & prayers.  You are fighting this with courage and great spirit. 

                                       

                                      Lori, caregiver to Will

                                      jag
                                      Participant

                                        Hey Kevin, the nice thing is to know that you haven't run out of treatment options.

                                        jag
                                        Participant

                                          Hey Kevin, the nice thing is to know that you haven't run out of treatment options.

                                            jag
                                            Participant

                                              Oops, hit the reply button to soon.  Best of Luck.

                                              John

                                              jag
                                              Participant

                                                Oops, hit the reply button to soon.  Best of Luck.

                                                John

                                                jag
                                                Participant

                                                  Oops, hit the reply button to soon.  Best of Luck.

                                                  John

                                                jag
                                                Participant

                                                  Hey Kevin, the nice thing is to know that you haven't run out of treatment options.

                                                  boot2aboot
                                                  Participant

                                                    If Zelboraf fails, you might consider a braf/mek combo…it is approved for prior braf users….more and more, i have come to realize we must not only act as advocates for ourselves but others suffering with the beast….

                                                    Phase II Trial of Mitogen Activated Protein (MAP) Kinase Inhibition With AZD6244 and MK-2206 (Akt Inhibitor) in Patients With Relapsed (BRAF) V600E Mutant Advanced MelanomaNCT01510444

                                                    exclusions: Patients with active central nervous system (CNS) metastases are excluded. Patients with a history of CNS metastasis that have been treated must be stable for 8 weeks after completion of treatment, with image documentation required.

                                                    Study of TAK-733 in Adult Patients With Advanced Nonhematologic Malignancies

                                                    NCT00948467

                                                    exclusions:Symptomatic brain metastases

                                                     

                                                    i don't know if your brain tumors are 'stable' and unsymptomatic, but if they are then there are two studies currently available when and if zelboraf fails

                                                    Please read my secondary cancer article also

                                                    boots

                                                    boot2aboot
                                                    Participant

                                                      If Zelboraf fails, you might consider a braf/mek combo…it is approved for prior braf users….more and more, i have come to realize we must not only act as advocates for ourselves but others suffering with the beast….

                                                      Phase II Trial of Mitogen Activated Protein (MAP) Kinase Inhibition With AZD6244 and MK-2206 (Akt Inhibitor) in Patients With Relapsed (BRAF) V600E Mutant Advanced MelanomaNCT01510444

                                                      exclusions: Patients with active central nervous system (CNS) metastases are excluded. Patients with a history of CNS metastasis that have been treated must be stable for 8 weeks after completion of treatment, with image documentation required.

                                                      Study of TAK-733 in Adult Patients With Advanced Nonhematologic Malignancies

                                                      NCT00948467

                                                      exclusions:Symptomatic brain metastases

                                                       

                                                      i don't know if your brain tumors are 'stable' and unsymptomatic, but if they are then there are two studies currently available when and if zelboraf fails

                                                      Please read my secondary cancer article also

                                                      boots

                                                        o2bcheri
                                                        Participant

                                                           

                                                          Hi Kevin,

                                                           

                                                          you are so young…  i don't know how you feel about alternative therapy… but… check out http://www.ncrf.org….

                                                          http://checkmedaily.com/health-beauty/diagnosed-no-evidence-of-cancer-treatment/ 

                                                           

                                                          some testimonials… if i had cancer… this is where i would run… have been reading up on it for a few weeks..

                                                          have it myself.. and for my daughter who has MS… my intuition tells me its the real thing…

                                                          good luck Kevin…  sending you many hugs and prayers…

                                                           

                                                          xx

                                                          o2bcheri
                                                          Participant

                                                             

                                                            Hi Kevin,

                                                             

                                                            you are so young…  i don't know how you feel about alternative therapy… but… check out http://www.ncrf.org….

                                                            http://checkmedaily.com/health-beauty/diagnosed-no-evidence-of-cancer-treatment/ 

                                                             

                                                            some testimonials… if i had cancer… this is where i would run… have been reading up on it for a few weeks..

                                                            have it myself.. and for my daughter who has MS… my intuition tells me its the real thing…

                                                            good luck Kevin…  sending you many hugs and prayers…

                                                             

                                                            xx

                                                            o2bcheri
                                                            Participant

                                                               

                                                              Hi Kevin,

                                                               

                                                              you are so young…  i don't know how you feel about alternative therapy… but… check out http://www.ncrf.org….

                                                              http://checkmedaily.com/health-beauty/diagnosed-no-evidence-of-cancer-treatment/ 

                                                               

                                                              some testimonials… if i had cancer… this is where i would run… have been reading up on it for a few weeks..

                                                              have it myself.. and for my daughter who has MS… my intuition tells me its the real thing…

                                                              good luck Kevin…  sending you many hugs and prayers…

                                                               

                                                              xx

                                                              jag
                                                              Participant

                                                                Kevin, if you are even considering looking at this crap, don't waste your time.  Another sleazebag hawking snake oil on the internet.  Don't get distracted and focus on your care.  

                                                                jag
                                                                Participant

                                                                  Kevin, if you are even considering looking at this crap, don't waste your time.  Another sleazebag hawking snake oil on the internet.  Don't get distracted and focus on your care.  

                                                                  jag
                                                                  Participant

                                                                    Kevin, if you are even considering looking at this crap, don't waste your time.  Another sleazebag hawking snake oil on the internet.  Don't get distracted and focus on your care.  

                                                                  boot2aboot
                                                                  Participant

                                                                    If Zelboraf fails, you might consider a braf/mek combo…it is approved for prior braf users….more and more, i have come to realize we must not only act as advocates for ourselves but others suffering with the beast….

                                                                    Phase II Trial of Mitogen Activated Protein (MAP) Kinase Inhibition With AZD6244 and MK-2206 (Akt Inhibitor) in Patients With Relapsed (BRAF) V600E Mutant Advanced MelanomaNCT01510444

                                                                    exclusions: Patients with active central nervous system (CNS) metastases are excluded. Patients with a history of CNS metastasis that have been treated must be stable for 8 weeks after completion of treatment, with image documentation required.

                                                                    Study of TAK-733 in Adult Patients With Advanced Nonhematologic Malignancies

                                                                    NCT00948467

                                                                    exclusions:Symptomatic brain metastases

                                                                     

                                                                    i don't know if your brain tumors are 'stable' and unsymptomatic, but if they are then there are two studies currently available when and if zelboraf fails

                                                                    Please read my secondary cancer article also

                                                                    boots

                                                                    davidfromsingapore
                                                                    Participant
                                                                      Kevin- you are going to beat this disease. The drugs are getting better each month. For example scientists just came out with a way to overcome Zelboraf’s resistance. Stay strong! David
                                                                      davidfromsingapore
                                                                      Participant
                                                                        Kevin- you are going to beat this disease. The drugs are getting better each month. For example scientists just came out with a way to overcome Zelboraf’s resistance. Stay strong! David
                                                                        davidfromsingapore
                                                                        Participant
                                                                          Kevin- you are going to beat this disease. The drugs are getting better each month. For example scientists just came out with a way to overcome Zelboraf’s resistance. Stay strong! David
                                                                          himynameiskevin
                                                                          Participant

                                                                            Thank you all for the replies, thoughts and information. I see a doctor in 6 hours about the results of Monday's brain MRI (hoping for stability and shrinkage, but if need be, another round of SRS would be fine, just praying nothing new is showing up, and hopefully get clearance to get off this steroid).  And in 7 1/2 hours, I'll be talking to another doctor about starting the Zelboraf. Big day. Hoping and praying for the best. -Kevin

                                                                            himynameiskevin
                                                                            Participant

                                                                              Thank you all for the replies, thoughts and information. I see a doctor in 6 hours about the results of Monday's brain MRI (hoping for stability and shrinkage, but if need be, another round of SRS would be fine, just praying nothing new is showing up, and hopefully get clearance to get off this steroid).  And in 7 1/2 hours, I'll be talking to another doctor about starting the Zelboraf. Big day. Hoping and praying for the best. -Kevin

                                                                              himynameiskevin
                                                                              Participant

                                                                                Thank you all for the replies, thoughts and information. I see a doctor in 6 hours about the results of Monday's brain MRI (hoping for stability and shrinkage, but if need be, another round of SRS would be fine, just praying nothing new is showing up, and hopefully get clearance to get off this steroid).  And in 7 1/2 hours, I'll be talking to another doctor about starting the Zelboraf. Big day. Hoping and praying for the best. -Kevin

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