WBR

  • Post
    evieg
    Participant

      Hi

      I read in a past post that Melanoma is radioresistant …. So chances are Whole Brain radiation is not very effective…. My husband just was told he has 24 tumors in his brain… Going to start on Monday.

      If you have any thought or input… It would be greatly appreciated.

      God Bless all of you.

      Evie

    Viewing 5 reply threads
    • Replies
        mrsaxde
        Participant

          I'm hoping for the best for your husband. Just curious, though. Why radiation, and not one of the immunotherapy drugs? (Yervoy, Keytruda, Opdivo) Or have they already been tried?

          mrsaxde
          Participant

            I'm hoping for the best for your husband. Just curious, though. Why radiation, and not one of the immunotherapy drugs? (Yervoy, Keytruda, Opdivo) Or have they already been tried?

              evieg
              Participant

                He has had 4 doses of Keytruda. He was supposed to have his 5 th dose tomorrow. Has been throwing up for the last month… On and off. Dr sent him for a Brain MRI yesterday.(had a brain MRI in May .. Two tiny nodules were there they said wait and recheck). Dr.said Ketruda not working…. ??? Was on Opdivo had Colitis switched to Keytruda… Cancer did spread to small bowel on Keytruda… (Also spread to spleen and lining of stomach on Opdivo) Now this blow out in the brain… Needless to say we are devastated . Nurse told me no more Keytruda.

                evieg
                Participant

                  He has had 4 doses of Keytruda. He was supposed to have his 5 th dose tomorrow. Has been throwing up for the last month… On and off. Dr sent him for a Brain MRI yesterday.(had a brain MRI in May .. Two tiny nodules were there they said wait and recheck). Dr.said Ketruda not working…. ??? Was on Opdivo had Colitis switched to Keytruda… Cancer did spread to small bowel on Keytruda… (Also spread to spleen and lining of stomach on Opdivo) Now this blow out in the brain… Needless to say we are devastated . Nurse told me no more Keytruda.

                  evieg
                  Participant

                    Thank you!

                     

                    evieg
                    Participant

                      Thank you!

                       

                      jamieth29
                      Participant
                        Is stereotactic or gamma knife a option? I dont know much about brain mets but there is a person on this site who’s mom had like 17-20 brain mets successfully treated by stereo or gamma knife
                        jamieth29
                        Participant
                          Is stereotactic or gamma knife a option? I dont know much about brain mets but there is a person on this site who’s mom had like 17-20 brain mets successfully treated by stereo or gamma knife
                          evieg
                          Participant

                            Dr said only option!!

                            evieg
                            Participant

                              Dr said only option!!

                              evieg
                              Participant

                                Dr said only option!!

                                jamieth29
                                Participant
                                  Is stereotactic or gamma knife a option? I dont know much about brain mets but there is a person on this site who’s mom had like 17-20 brain mets successfully treated by stereo or gamma knife
                                  evieg
                                  Participant

                                    Thank you!

                                     

                                    evieg
                                    Participant

                                      He has had 4 doses of Keytruda. He was supposed to have his 5 th dose tomorrow. Has been throwing up for the last month… On and off. Dr sent him for a Brain MRI yesterday.(had a brain MRI in May .. Two tiny nodules were there they said wait and recheck). Dr.said Ketruda not working…. ??? Was on Opdivo had Colitis switched to Keytruda… Cancer did spread to small bowel on Keytruda… (Also spread to spleen and lining of stomach on Opdivo) Now this blow out in the brain… Needless to say we are devastated . Nurse told me no more Keytruda.

                                    mrsaxde
                                    Participant

                                      I'm hoping for the best for your husband. Just curious, though. Why radiation, and not one of the immunotherapy drugs? (Yervoy, Keytruda, Opdivo) Or have they already been tried?

                                      Bubbles
                                      Participant

                                        Hi Evie, 

                                        So sorry for what you and your husband are dealing with. I'm guessing your husband is BRAF negative since you didn't mention his having used BRAF inhibitors. But, that is one thing you might consider if possible. At any rate, here is a post that covers a review of brain met management and links within to other brain met info. I realize your husband has already been through a great deal and this may be of little help to you. 

                                        http://chaoticallypreciselifeloveandmelanoma.blogspot.com/2015/07/a-really-good-review-of-treatment-data.html

                                        Sorry I don't have more to offer. Mostly just wanted to let you know that I am thinking of you and wishing you well. Celeste

                                         

                                          evieg
                                          Participant

                                            Celeste, 

                                             Thank you very much!   Met with Melanoma specialist today… Said after WBR , she wants my husband to do 

                                            Biochemotherapy.  Has done it all IL-2, Ippi, Opdivo, and Keytruda..said BioChemo or Hospice.

                                            My husband is Braf negative.  BIO chemo  dr said… 60% response rate…. Only 7-10%  become NED.

                                            So not looking too good. He will continue to fight.

                                            thanks again

                                            evieg
                                            Participant

                                              Celeste, 

                                               Thank you very much!   Met with Melanoma specialist today… Said after WBR , she wants my husband to do 

                                              Biochemotherapy.  Has done it all IL-2, Ippi, Opdivo, and Keytruda..said BioChemo or Hospice.

                                              My husband is Braf negative.  BIO chemo  dr said… 60% response rate…. Only 7-10%  become NED.

                                              So not looking too good. He will continue to fight.

                                              thanks again

                                              evieg
                                              Participant

                                                Celeste, 

                                                 Thank you very much!   Met with Melanoma specialist today… Said after WBR , she wants my husband to do 

                                                Biochemotherapy.  Has done it all IL-2, Ippi, Opdivo, and Keytruda..said BioChemo or Hospice.

                                                My husband is Braf negative.  BIO chemo  dr said… 60% response rate…. Only 7-10%  become NED.

                                                So not looking too good. He will continue to fight.

                                                thanks again

                                                evieg
                                                Participant

                                                  Celeste, 

                                                   Thank you very much!   Met with Melanoma specialist today… Said after WBR , she wants my husband to do 

                                                  Biochemotherapy.  Has done it all IL-2, Ippi, Opdivo, and Keytruda..said BioChemo or Hospice.

                                                  My husband is Braf negative.  BIO chemo  dr said… 60% response rate…. Only 7-10%  become NED.

                                                  So not looking too good. He will continue to fight.

                                                  thanks again

                                                  evieg
                                                  Participant

                                                    Celeste, 

                                                     Thank you very much!   Met with Melanoma specialist today… Said after WBR , she wants my husband to do 

                                                    Biochemotherapy.  Has done it all IL-2, Ippi, Opdivo, and Keytruda..said BioChemo or Hospice.

                                                    My husband is Braf negative.  BIO chemo  dr said… 60% response rate…. Only 7-10%  become NED.

                                                    So not looking too good. He will continue to fight.

                                                    thanks again

                                                    evieg
                                                    Participant

                                                      Celeste, 

                                                       Thank you very much!   Met with Melanoma specialist today… Said after WBR , she wants my husband to do 

                                                      Biochemotherapy.  Has done it all IL-2, Ippi, Opdivo, and Keytruda..said BioChemo or Hospice.

                                                      My husband is Braf negative.  BIO chemo  dr said… 60% response rate…. Only 7-10%  become NED.

                                                      So not looking too good. He will continue to fight.

                                                      thanks again

                                                    Bubbles
                                                    Participant

                                                      Hi Evie, 

                                                      So sorry for what you and your husband are dealing with. I'm guessing your husband is BRAF negative since you didn't mention his having used BRAF inhibitors. But, that is one thing you might consider if possible. At any rate, here is a post that covers a review of brain met management and links within to other brain met info. I realize your husband has already been through a great deal and this may be of little help to you. 

                                                      http://chaoticallypreciselifeloveandmelanoma.blogspot.com/2015/07/a-really-good-review-of-treatment-data.html

                                                      Sorry I don't have more to offer. Mostly just wanted to let you know that I am thinking of you and wishing you well. Celeste

                                                       

                                                      Bubbles
                                                      Participant

                                                        Hi Evie, 

                                                        So sorry for what you and your husband are dealing with. I'm guessing your husband is BRAF negative since you didn't mention his having used BRAF inhibitors. But, that is one thing you might consider if possible. At any rate, here is a post that covers a review of brain met management and links within to other brain met info. I realize your husband has already been through a great deal and this may be of little help to you. 

                                                        http://chaoticallypreciselifeloveandmelanoma.blogspot.com/2015/07/a-really-good-review-of-treatment-data.html

                                                        Sorry I don't have more to offer. Mostly just wanted to let you know that I am thinking of you and wishing you well. Celeste

                                                         

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