V600D and Zelboraf with cardiac met

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    • June 3, 2012 at 10:37 pm
    awillett1991
    Participant
      Doe anyone know of any success with Zelboraf and.the v600D mutation outside of a petri dish. I have a cardiac met and could not get into several trials because of it, or the D mutation. I’m on a reduced 720 mg dose because of the side effects, including grade 4 allergic reaction (rash) on the full dose and just getting discouraged waiting to find out if it’s even effective. Fortunately my doc is involved with the trials and knows the drug well, just not sure Vandy has any another v600D mutations. Of course I’m grateful that I’m allowed to try it when so many aren’t.

      Doe anyone know of any success with Zelboraf and.the v600D mutation outside of a petri dish. I have a cardiac met and could not get into several trials because of it, or the D mutation. I’m on a reduced 720 mg dose because of the side effects, including grade 4 allergic reaction (rash) on the full dose and just getting discouraged waiting to find out if it’s even effective. Fortunately my doc is involved with the trials and knows the drug well, just not sure Vandy has any another v600D mutations. Of course I’m grateful that I’m allowed to try it when so many aren’t. What about Zelboraf and heart tumors??

      Thanks!

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