› Forums › General Melanoma Community › New BMS Anti-PD1 trial info, 50% IPI failures
- This topic has 12 replies, 2 voices, and was last updated 13 years, 7 months ago by
LynnLuc.
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- July 5, 2012 at 8:27 pm
http://clinicaltrials.gov/ct2/show/NCT01621490My onc mentioned this last week. I know it’s all about the timingand it won’t be for me. Not much info here but interesting they are looking for half the patients to have failed IPI. I do get frustrated with the entire clinical trials exclusion process but at least some can be helped. If I were a candidate, I’d start making phone calls!
~Peace
http://clinicaltrials.gov/ct2/show/NCT01621490
My onc mentioned this last week. I know it’s all about the timingand it won’t be for me. Not much info here but interesting they are looking for half the patients to have failed IPI. I do get frustrated with the entire clinical trials exclusion process but at least some can be helped. If I were a candidate, I’d start making phone calls!
~Peace
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- July 5, 2012 at 10:55 pm
The bio marker is PDL1…they are thinking that if the melanoma doesn't have it- the anti pd-1 will not work-period…knowing if this is true or notwill save many people precious time instead of doing treatment that will not work, Around 110 people from Moffittin the BMS trial have been signing releases so our melanoma can be tested to see if in fact we have the PDL1.BMS is doing the testing. Currently they are not excluding anyone from the trial that does not have the PDL1.
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- July 5, 2012 at 10:55 pm
The bio marker is PDL1…they are thinking that if the melanoma doesn't have it- the anti pd-1 will not work-period…knowing if this is true or notwill save many people precious time instead of doing treatment that will not work, Around 110 people from Moffittin the BMS trial have been signing releases so our melanoma can be tested to see if in fact we have the PDL1.BMS is doing the testing. Currently they are not excluding anyone from the trial that does not have the PDL1.
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- July 6, 2012 at 12:51 am
My understanding is that half (50%) of the people they are taking must have already failed IPI. I think they’ve always been excluded before from Anti pd1 and Anti pdl1. So for some lucky 40 people, this is big news. -
- July 6, 2012 at 12:51 am
My understanding is that half (50%) of the people they are taking must have already failed IPI. I think they’ve always been excluded before from Anti pd1 and Anti pdl1. So for some lucky 40 people, this is big news. -
- July 8, 2012 at 6:11 am
I never did IPI and I am in the BMS Anti PD 1 trial. Moffitt has an arm of the trial that permits prior use of IPI. Here is a great trial using both…Dose-escalation Study of Combination BMS-936558 (MDX-1106) and Ipilimumab in Subjects With Unresectable Stage III or Stage IV Malignant Melanoma
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- July 8, 2012 at 6:11 am
I never did IPI and I am in the BMS Anti PD 1 trial. Moffitt has an arm of the trial that permits prior use of IPI. Here is a great trial using both…Dose-escalation Study of Combination BMS-936558 (MDX-1106) and Ipilimumab in Subjects With Unresectable Stage III or Stage IV Malignant Melanoma
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- July 8, 2012 at 6:11 am
I never did IPI and I am in the BMS Anti PD 1 trial. Moffitt has an arm of the trial that permits prior use of IPI. Here is a great trial using both…Dose-escalation Study of Combination BMS-936558 (MDX-1106) and Ipilimumab in Subjects With Unresectable Stage III or Stage IV Malignant Melanoma
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- July 6, 2012 at 12:51 am
My understanding is that half (50%) of the people they are taking must have already failed IPI. I think they’ve always been excluded before from Anti pd1 and Anti pdl1. So for some lucky 40 people, this is big news.
-
- July 5, 2012 at 10:55 pm
The bio marker is PDL1…they are thinking that if the melanoma doesn't have it- the anti pd-1 will not work-period…knowing if this is true or notwill save many people precious time instead of doing treatment that will not work, Around 110 people from Moffittin the BMS trial have been signing releases so our melanoma can be tested to see if in fact we have the PDL1.BMS is doing the testing. Currently they are not excluding anyone from the trial that does not have the PDL1.
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