IPI and abdominal pain

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  • Post
    • August 16, 2011 at 2:47 am
    mclaus23
    Participant

      Hi All,

       

      My dad, Stage IV mel with mets in the adrenal glands, began ipi 5 days ago. He is in extreme abdominal pain and had night sweats last night. Dr says this is an indication the ipi is working. Has anyone here had  this experience?

      He also said the tumor on his groin is slightly inflamed and sensitive to touch.

       

      Thanks in advance for your input!

      Maggie

      Hi All,

       

      My dad, Stage IV mel with mets in the adrenal glands, began ipi 5 days ago. He is in extreme abdominal pain and had night sweats last night. Dr says this is an indication the ipi is working. Has anyone here had  this experience?

      He also said the tumor on his groin is slightly inflamed and sensitive to touch.

       

      Thanks in advance for your input!

      Maggie

    Viewing 5 reply threads
    • Replies
        • August 16, 2011 at 11:40 am
        Lisa13
        Participant

          Hi Maggie,

          That is definately a quick response!  I just started ipi as well 6 days ago and have experienced nothing. My Dr. said I shouldn't feel any side effects this early, but everyone is different.  I really hope this is a good indication that the ipi is working for your Dad. 

          Best of luck!

          Lisa

          • August 16, 2011 at 11:40 am
          Lisa13
          Participant

            Hi Maggie,

            That is definately a quick response!  I just started ipi as well 6 days ago and have experienced nothing. My Dr. said I shouldn't feel any side effects this early, but everyone is different.  I really hope this is a good indication that the ipi is working for your Dad. 

            Best of luck!

            Lisa

            • August 16, 2011 at 2:56 pm
            KatyWI
            Participant

              Abdominal pain can be a side effect of ipi and can indicate colitis.  There does appear to be an association between occurence of side effects and response.  Regardless, "extreme" abdominal pain still needs to be addressed.  Is the doctor doing anything about his pain?

              KatyWI

              • August 16, 2011 at 2:56 pm
              KatyWI
              Participant

                Abdominal pain can be a side effect of ipi and can indicate colitis.  There does appear to be an association between occurence of side effects and response.  Regardless, "extreme" abdominal pain still needs to be addressed.  Is the doctor doing anything about his pain?

                KatyWI

                • August 16, 2011 at 11:15 pm
                Dynasysman
                Participant

                  Hi Maggie —

                  A week into IPI therapy, I began to experience a fairly strong rash on my forearms.  The next day, we excised a tumor from my neck.  Pathology showed strongly increased lymphocyte presence and only a small area of focal activity (I think that means my white cells were killing the tumor).

                  From what I understand, tumors responding to ipi can swell for a while as the white cells arrive to fight the melanoma.  His results may actually be quite encouraging.

                  Best of luck and wishes of success for him, and for you.

                  • August 16, 2011 at 11:15 pm
                  Dynasysman
                  Participant

                    Hi Maggie —

                    A week into IPI therapy, I began to experience a fairly strong rash on my forearms.  The next day, we excised a tumor from my neck.  Pathology showed strongly increased lymphocyte presence and only a small area of focal activity (I think that means my white cells were killing the tumor).

                    From what I understand, tumors responding to ipi can swell for a while as the white cells arrive to fight the melanoma.  His results may actually be quite encouraging.

                    Best of luck and wishes of success for him, and for you.

                      • August 16, 2011 at 11:43 pm
                      mclaus23
                      Participant

                        I thank everyone for your input and help!

                        We greatly appreciate it.

                        As of right now he feels much better than yesterday, though very tired. The abdominal pain has diminished greatly. He said he had never experienced pain like that in his life.

                        I wish you all the best of luck, I'm praying for you all!
                        Definitely keep me informed on your journey with ipi

                         

                        PS- You WILL make your anniversary!!! 

                        • August 16, 2011 at 11:43 pm
                        mclaus23
                        Participant

                          I thank everyone for your input and help!

                          We greatly appreciate it.

                          As of right now he feels much better than yesterday, though very tired. The abdominal pain has diminished greatly. He said he had never experienced pain like that in his life.

                          I wish you all the best of luck, I'm praying for you all!
                          Definitely keep me informed on your journey with ipi

                           

                          PS- You WILL make your anniversary!!! 

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