How long before Keytruda treatment is considered “failed?”

Forums General Melanoma Community How long before Keytruda treatment is considered “failed?”

  • Post
    lesli
    Participant

      Hi All,  my scans at 7.5 weeks on Keytruda are showing universal growth in all lesioins.  In all hope, could it be inflammation?  How long to proceed treatment before considering another option (there is still a question about what that is)?  That is, what is the definition of "failed" on Keytruda?

      Thanks in advance. Leslie

    Viewing 2 reply threads
    • Replies
        arthurjedi007
        Participant

          So you probably have had 3 doses at that time. If your tumor burden is ok so you can give it more time and you feel ok I would give it 2 or preferably 3 more doses. Immunotherapy takes time to work and yes that could be the med causing swelling. On the flip side though at that same time they said I had 19 of 30 tumors shrinking. So it is a really tough call to make. What other treatment options are they offering? I'm curious because I've had 16 doses and my 3rd pd1 scan is tomorrow and the doc is already talking about the ERK treatment for me.

          Artie

            lesli
            Participant

              Hi Artie,

              Thank you for your reply.  Your last question about treatment options is a good one–I'm blowing through the standard treatments pretty quickly.. TIL treatment has been mentioned, with a mixed report. A very intense treatment that requires ICU care.

              What is the ERK treatment you mention? That is new to me.

              What country are you in and/or region of the states?

              Leslie

              arthurjedi007
              Participant

                ERK is pills like the braf except I don't think you have to have the braf mutation. I'm in saint Louis.

                Artie

                _Paul_
                Participant

                  Good luck with your scans today Artie!

                  _Paul_
                  Participant

                    Good luck with your scans today Artie!

                    _Paul_
                    Participant

                      Good luck with your scans today Artie!

                      arthurjedi007
                      Participant

                        ERK is pills like the braf except I don't think you have to have the braf mutation. I'm in saint Louis.

                        Artie

                        arthurjedi007
                        Participant

                          ERK is pills like the braf except I don't think you have to have the braf mutation. I'm in saint Louis.

                          Artie

                          lesli
                          Participant

                            Hi Artie,

                            Thank you for your reply.  Your last question about treatment options is a good one–I'm blowing through the standard treatments pretty quickly.. TIL treatment has been mentioned, with a mixed report. A very intense treatment that requires ICU care.

                            What is the ERK treatment you mention? That is new to me.

                            What country are you in and/or region of the states?

                            Leslie

                            lesli
                            Participant

                              Hi Artie,

                              Thank you for your reply.  Your last question about treatment options is a good one–I'm blowing through the standard treatments pretty quickly.. TIL treatment has been mentioned, with a mixed report. A very intense treatment that requires ICU care.

                              What is the ERK treatment you mention? That is new to me.

                              What country are you in and/or region of the states?

                              Leslie

                            arthurjedi007
                            Participant

                              So you probably have had 3 doses at that time. If your tumor burden is ok so you can give it more time and you feel ok I would give it 2 or preferably 3 more doses. Immunotherapy takes time to work and yes that could be the med causing swelling. On the flip side though at that same time they said I had 19 of 30 tumors shrinking. So it is a really tough call to make. What other treatment options are they offering? I'm curious because I've had 16 doses and my 3rd pd1 scan is tomorrow and the doc is already talking about the ERK treatment for me.

                              Artie

                              arthurjedi007
                              Participant

                                So you probably have had 3 doses at that time. If your tumor burden is ok so you can give it more time and you feel ok I would give it 2 or preferably 3 more doses. Immunotherapy takes time to work and yes that could be the med causing swelling. On the flip side though at that same time they said I had 19 of 30 tumors shrinking. So it is a really tough call to make. What other treatment options are they offering? I'm curious because I've had 16 doses and my 3rd pd1 scan is tomorrow and the doc is already talking about the ERK treatment for me.

                                Artie

                            Viewing 2 reply threads
                            • You must be logged in to reply to this topic.
                            About the MRF Patient Forum

                            The MRF Patient Forum is the oldest and largest online community of people affected by melanoma. It is designed to provide peer support and information to caregivers, patients, family and friends. There is no better place to discuss different parts of your journey with this cancer and find the friends and support resources to make that journey more bearable.

                            The information on the forum is open and accessible to everyone. To add a new topic or to post a reply, you must be a registered user. Please note that you will be able to post both topics and replies anonymously even though you are logged in. All posts must abide by MRF posting policies.

                            Popular Topics