Hi everyone,
As many already know, I have been on Zelboraf, intermittent dosing, since the beginning of the year. Three weeks on, two weeks off.
During the last off period, previously-flattened (meaning disease-free) mets on scalp/ear began growing again.
Hi everyone,
As many already know, I have been on Zelboraf, intermittent dosing, since the beginning of the year. Three weeks on, two weeks off.
During the last off period, previously-flattened (meaning disease-free) mets on scalp/ear began growing again.
As some also know, I’ve been trying to get into an anti PD1 trial for close to 2 years now. The restrictions have always stopped me, or when a new trial opened, I didn’t have the measurable disease required, having been a partial responder to several therapies. So when I had this “progression”, which halted upon resuming Zel, I photographed it & sent to onc. We decided together that since this will LIKELY turn into measurable disease, to stop Zel yesterday. MRI of brain & CT of chest & abdomen scheduled for 2 weeks from today. he said MRI should pick up measurable disease. I just feel that now is the time, because if PD1 fails me, I still have working Zel in my back pocket. Of course I’m second-guessing myself that I should have started last week, etc. etc. I guess that if after 2weeks they’re growing but not to 1cm required, I can postpone a week. But as our beloved Boots used to say: Don’t Look Back; Don’t Back Down.
That’s my story and I’m sticking to it, albeit nervously.
Karen
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