Has anyone received a flu shot while on these drugs and did you have any problems from it? I see my dr on friday and can ask him then, I looked on line but did not find much and then some said you could some said you can't.
I got one, was fine, my oncologist is fine with it, I know others have gotten them too. Guess some doctors have different opinions, see what yours says about it.
I got one, was fine, my oncologist is fine with it, I know others have gotten them too. Guess some doctors have different opinions, see what yours says about it.
I got one, was fine, my oncologist is fine with it, I know others have gotten them too. Guess some doctors have different opinions, see what yours says about it.
"Bristol-Myers Squibb (BMS), the maker of ipilimumab and nivolumab, suggested to Medscape Medical News that there is not a definitive answer about the safety and efficacy of the flu vaccine in patients on their drugs.
About ipilimumab, company spokesperson Carrie Fernandez said in an email: "Controlled clinical trials have not been conducted to investigate the combination of influenza vaccines with ipilimumab."
However, there are some data on the activity of the flu vaccine in ipilimumab-treated patients.
According to a BMS summary, some patients in a phase 2 study received an influenza vaccine after the first ipilimumab dose for the treatment of advanced melanoma (J Immunother. 2012;35:89-97). Most vaccinated patients had an increase in antibody levels (humoral response) to influenza B, A/H1N1, A/H3N2 antigens, whereas most nonvaccinated patients showed no response. In other words, there is some evidence that the flu shot produces an immune response in some ipilimumab-treated patients."
I think I would want vaccine unless doc could give compelling reason not to take.
"Bristol-Myers Squibb (BMS), the maker of ipilimumab and nivolumab, suggested to Medscape Medical News that there is not a definitive answer about the safety and efficacy of the flu vaccine in patients on their drugs.
About ipilimumab, company spokesperson Carrie Fernandez said in an email: "Controlled clinical trials have not been conducted to investigate the combination of influenza vaccines with ipilimumab."
However, there are some data on the activity of the flu vaccine in ipilimumab-treated patients.
According to a BMS summary, some patients in a phase 2 study received an influenza vaccine after the first ipilimumab dose for the treatment of advanced melanoma (J Immunother. 2012;35:89-97). Most vaccinated patients had an increase in antibody levels (humoral response) to influenza B, A/H1N1, A/H3N2 antigens, whereas most nonvaccinated patients showed no response. In other words, there is some evidence that the flu shot produces an immune response in some ipilimumab-treated patients."
I think I would want vaccine unless doc could give compelling reason not to take.
"Bristol-Myers Squibb (BMS), the maker of ipilimumab and nivolumab, suggested to Medscape Medical News that there is not a definitive answer about the safety and efficacy of the flu vaccine in patients on their drugs.
About ipilimumab, company spokesperson Carrie Fernandez said in an email: "Controlled clinical trials have not been conducted to investigate the combination of influenza vaccines with ipilimumab."
However, there are some data on the activity of the flu vaccine in ipilimumab-treated patients.
According to a BMS summary, some patients in a phase 2 study received an influenza vaccine after the first ipilimumab dose for the treatment of advanced melanoma (J Immunother. 2012;35:89-97). Most vaccinated patients had an increase in antibody levels (humoral response) to influenza B, A/H1N1, A/H3N2 antigens, whereas most nonvaccinated patients showed no response. In other words, there is some evidence that the flu shot produces an immune response in some ipilimumab-treated patients."
I think I would want vaccine unless doc could give compelling reason not to take.
My doc was fine with it, post Yervoy and several months into Keytruda. YMMV.
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