Combinatorial Yervoy + BRAF Therapy… When?

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  • Post
    • July 22, 2011 at 1:32 pm
    jim Breitfeller
    Participant

      I just got word that Combinatorial …Yervoy + BRAF Therapy.. is coming

      "t's being assembled. First patients treated sometime in the fall."

      This is from a reliable source.

      Jimmy B

      I just got word that Combinatorial …Yervoy + BRAF Therapy.. is coming

      "t's being assembled. First patients treated sometime in the fall."

      This is from a reliable source.

      Jimmy B

    Viewing 5 reply threads
    • Replies
        • July 22, 2011 at 1:42 pm
        sharmon
        Participant

          That is great news!  Brent has failed ipi and we would like to get information on anti PD-1.  If you have any news on when they might let folks who have failed ipi try PD-1 would you pass it on also.  They are excluding prior ipi patients now but I would hope someday….Thanks

          • July 22, 2011 at 1:42 pm
          sharmon
          Participant

            That is great news!  Brent has failed ipi and we would like to get information on anti PD-1.  If you have any news on when they might let folks who have failed ipi try PD-1 would you pass it on also.  They are excluding prior ipi patients now but I would hope someday….Thanks

            • July 22, 2011 at 2:47 pm
            killmel
            Participant

              Hi Jimmy,

               

              Thank you for the update.

              I have read speculation that BMS is not scheduled for trials just using anti-pd1 trial for patients who have not done IPI because of FDA approval yervoy.

              I know that there are  trials using anti-pd1 drug as a stand ALONE drug but I have called location sites doing the trial & these sites are not recruiting.

              Considering that anti-pd1 has been reported as an effective drug with less side effects, I know people areinterested in taking this  drug

              I know that you have great sources…any information on future trials using anti-pd1 drug as a stand ALONE drug.

               

              Jimmy aprreciate all your insight & help.

              • July 22, 2011 at 2:47 pm
              killmel
              Participant

                Hi Jimmy,

                 

                Thank you for the update.

                I have read speculation that BMS is not scheduled for trials just using anti-pd1 trial for patients who have not done IPI because of FDA approval yervoy.

                I know that there are  trials using anti-pd1 drug as a stand ALONE drug but I have called location sites doing the trial & these sites are not recruiting.

                Considering that anti-pd1 has been reported as an effective drug with less side effects, I know people areinterested in taking this  drug

                I know that you have great sources…any information on future trials using anti-pd1 drug as a stand ALONE drug.

                 

                Jimmy aprreciate all your insight & help.

                  • July 22, 2011 at 5:35 pm
                  jim Breitfeller
                  Participant

                     PD-1 antibody: CT011, BMS936558.

                     

                    Clinical results are projected  in the fouth quater of 2013

                    • July 22, 2011 at 5:35 pm
                    jim Breitfeller
                    Participant

                       PD-1 antibody: CT011, BMS936558.

                       

                      Clinical results are projected  in the fouth quater of 2013

                      • July 23, 2011 at 1:03 am
                      LynnLuc
                      Participant

                        Hi Jimmy,

                        I know my Doc says  if I had done Ipi preveiously I wouldn't have gotten into an Anti PD 1 trial. Lynn

                        • July 23, 2011 at 1:03 am
                        LynnLuc
                        Participant

                          Hi Jimmy,

                          I know my Doc says  if I had done Ipi preveiously I wouldn't have gotten into an Anti PD 1 trial. Lynn

                        • July 23, 2011 at 11:34 am
                        MariaH
                        Participant

                          Very, very good news!!  Thanks Jim!

                            • July 23, 2011 at 5:09 pm
                            killmel
                            Participant

                              Jimmy,

                               

                              Thank you so much for passing on valuable information from your sources.

                              I realize there are presently these trials testing anti-pd1 and pdl-1 but when I called the site locations they are no longer recruiting:

                              http://clinicaltrials.gov/ct2/show/NCT00729664

                              http://clinicaltrials.gov/ct2/show/NCT00730639

                               Do any of your sources have any information on "NEW" future trials for MELANOMA patients using anti-pd1 drug or anti-pdl1 as a the trial drug with NO combination of any other drug (s) just  anti-pd1 drug or anti-pdl1 for melanoma patients that have NOT take IPI?

                              I have not taken IPI & prefer to particiapte in a trial using anti-pd1 drug or anti-pdl1 as a the trial drug with NO combination of any other drug (s).

                              Anyone know if there are any "NEW" future trials for MELANOMA patients using anti-pd1 drug or anti-pdl1 as a the trial drug with NO combination of any other drug (s) just  anti-pd1 drug or anti-pdl1 for melanoma patients that have NOT take IPI?

                              Thanks for reading my post

                              • July 23, 2011 at 5:09 pm
                              killmel
                              Participant

                                Jimmy,

                                 

                                Thank you so much for passing on valuable information from your sources.

                                I realize there are presently these trials testing anti-pd1 and pdl-1 but when I called the site locations they are no longer recruiting:

                                http://clinicaltrials.gov/ct2/show/NCT00729664

                                http://clinicaltrials.gov/ct2/show/NCT00730639

                                 Do any of your sources have any information on "NEW" future trials for MELANOMA patients using anti-pd1 drug or anti-pdl1 as a the trial drug with NO combination of any other drug (s) just  anti-pd1 drug or anti-pdl1 for melanoma patients that have NOT take IPI?

                                I have not taken IPI & prefer to particiapte in a trial using anti-pd1 drug or anti-pdl1 as a the trial drug with NO combination of any other drug (s).

                                Anyone know if there are any "NEW" future trials for MELANOMA patients using anti-pd1 drug or anti-pdl1 as a the trial drug with NO combination of any other drug (s) just  anti-pd1 drug or anti-pdl1 for melanoma patients that have NOT take IPI?

                                Thanks for reading my post

                                • July 23, 2011 at 5:58 pm
                                jim Breitfeller
                                Participant

                                   

                                  I contacted  an Oncologist  and the hes said"

                                  "Trial at Mayo and San Antonio (START), and another  similar study at Wayne State and Nashville.

                                   Prior ipi probably excludes."

                                   

                                  I hope this helps

                                   

                                  Jimmy B

                                  • July 23, 2011 at 5:58 pm
                                  jim Breitfeller
                                  Participant

                                     

                                    I contacted  an Oncologist  and the hes said"

                                    "Trial at Mayo and San Antonio (START), and another  similar study at Wayne State and Nashville.

                                     Prior ipi probably excludes."

                                     

                                    I hope this helps

                                     

                                    Jimmy B

                                    • July 23, 2011 at 9:51 pm
                                    killmel
                                    Participant

                                      Thanks Jimmy…any clinical trial "NCT" number so I can look it up & get contact information.are not on the westcoast.

                                      I am disappointed that none anti pd1 &pdl-1 trials are on the WET Coast.

                                      • July 23, 2011 at 9:51 pm
                                      killmel
                                      Participant

                                        Thanks Jimmy…any clinical trial "NCT" number so I can look it up & get contact information.are not on the westcoast.

                                        I am disappointed that none anti pd1 &pdl-1 trials are on the WET Coast.

                                        • October 2, 2011 at 9:54 pm
                                        LuckyMan51
                                        Participant

                                          i am told that memorial sloan kettering will likely be involved in an anti pd1 trial this fall (2011).  my source was unsure if it was standalone or in combination. good luck…

                                          • October 2, 2011 at 9:54 pm
                                          LuckyMan51
                                          Participant

                                            i am told that memorial sloan kettering will likely be involved in an anti pd1 trial this fall (2011).  my source was unsure if it was standalone or in combination. good luck…

                                          • July 23, 2011 at 11:34 am
                                          MariaH
                                          Participant

                                            Very, very good news!!  Thanks Jim!

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