BRAF Drug – confusing results

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    • May 18, 2011 at 2:23 pm
    emilypen
    Participant

      Hi All,

       My husband just had his 6 week scan after starting on PLX4032, the Roche Braf inhibitor. He had to be taken off for a 4 days during the last 2 weeks due to side effects, but had been back on the drugs at a reduced dose for the last week before the scans.

      Apparently they show a slight progression, the doctor said he's calling it "stable" for now, and wants to check again in 3 weeks.

      Jay had been on a MEK inhibitor previously and the docs were worried there might be some drug resistance to the Braf inhibitor becasue of that.

      Hi All,

       My husband just had his 6 week scan after starting on PLX4032, the Roche Braf inhibitor. He had to be taken off for a 4 days during the last 2 weeks due to side effects, but had been back on the drugs at a reduced dose for the last week before the scans.

      Apparently they show a slight progression, the doctor said he's calling it "stable" for now, and wants to check again in 3 weeks.

      Jay had been on a MEK inhibitor previously and the docs were worried there might be some drug resistance to the Braf inhibitor becasue of that.

      Did anyone else have a similar "stable" scan after taking the drug for 6 weeks and if so, what happened next?

      We were so hoping we'd get at least 6 months out of this drug before moving on to the next.

       

      thanks,

      Emily

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