› Forums › General Melanoma Community › braf after zelboraf
- This topic has 15 replies, 2 voices, and was last updated 14 years, 2 months ago by
deardad.
- Post
-
- November 30, 2011 at 7:42 pm
Could anyone on this forum tell me is Mek trial is effective after zelboraf?
I have read that braf/mek combos are effective treatments.
Can people still participate in Braf/Mek trials after taking zelboraf?
Could anyone on this forum tell me is Mek trial is effective after zelboraf?
I have read that braf/mek combos are effective treatments.
Can people still participate in Braf/Mek trials after taking zelboraf?
- Replies
-
-
- December 1, 2011 at 3:29 am
Hi I am also interesting in answers on this topic. My dad is on Zelboraf month 3 and we feel like sitting ducks. The onocologist did mention that we could try MEK next, but I don't know why they didn't just give him the combination in the first place? What is next after Zelboraf or is that the last card?
Nahmi from Melbourne
-
- December 1, 2011 at 3:29 am
Hi I am also interesting in answers on this topic. My dad is on Zelboraf month 3 and we feel like sitting ducks. The onocologist did mention that we could try MEK next, but I don't know why they didn't just give him the combination in the first place? What is next after Zelboraf or is that the last card?
Nahmi from Melbourne
-
- December 1, 2011 at 11:35 am
Nahmi, here is a link to the MEK trials in Australia:
http://www.clinicaltrials.gov/ct2/results?term=melanoma+MEK+Inhibitor&recr=Open&cntry1=PA%3AAUYour dad's oncologist is probably hesitant to recommend any new drug that hasn't been
approved by the TGA. As you may know, Yervoy has recently been approved here and the
oncologist should be able to tell you how your dad could have access to it.Some other viable options could be IL-2 (interleukin-2), TIL treatment (adoptive cell
therapy) and Anti PD-1 treatment. However, these may be unavailable locally and some may
only be accessed through clinical trials.Therefore, it is important to make definite plans for the next treatment if the current one
becomes ineffective.Hope this helps.
Frank from Australia
-
- December 1, 2011 at 11:35 am
Nahmi, here is a link to the MEK trials in Australia:
http://www.clinicaltrials.gov/ct2/results?term=melanoma+MEK+Inhibitor&recr=Open&cntry1=PA%3AAUYour dad's oncologist is probably hesitant to recommend any new drug that hasn't been
approved by the TGA. As you may know, Yervoy has recently been approved here and the
oncologist should be able to tell you how your dad could have access to it.Some other viable options could be IL-2 (interleukin-2), TIL treatment (adoptive cell
therapy) and Anti PD-1 treatment. However, these may be unavailable locally and some may
only be accessed through clinical trials.Therefore, it is important to make definite plans for the next treatment if the current one
becomes ineffective.Hope this helps.
Frank from Australia
-
- December 1, 2011 at 11:35 am
Nahmi, here is a link to the MEK trials in Australia:
http://www.clinicaltrials.gov/ct2/results?term=melanoma+MEK+Inhibitor&recr=Open&cntry1=PA%3AAUYour dad's oncologist is probably hesitant to recommend any new drug that hasn't been
approved by the TGA. As you may know, Yervoy has recently been approved here and the
oncologist should be able to tell you how your dad could have access to it.Some other viable options could be IL-2 (interleukin-2), TIL treatment (adoptive cell
therapy) and Anti PD-1 treatment. However, these may be unavailable locally and some may
only be accessed through clinical trials.Therefore, it is important to make definite plans for the next treatment if the current one
becomes ineffective.Hope this helps.
Frank from Australia
-
- December 2, 2011 at 7:16 am
Nahmi, I think that you will need to research the treatments for your dad. This will need a lot of work, but I think that it is necessary.
The Net makes it easier to find out where various treatments are available. However, you will also have to contact various treatment centres by phone and/or email to get more info.
You would also need to ring his oncologist to talk about this. A second opinion could also be an idea.
As you might know, I am also located in Melbourne. However, I don't know if that helps at all.
Take care
Frank from Australia
-
- December 2, 2011 at 8:20 am
Ok thanks, I will do some research. Im keen to find out about Antipd1 trial if there are any in Australia. I know Jim Stynes who being treated by my dad's oncologist is on this drug. From what I understand TIL requires you to be under the age of 60. I will ask the oncologist about this in 2 weeks. Thanks again.
Nahmi
-
- December 2, 2011 at 8:20 am
Ok thanks, I will do some research. Im keen to find out about Antipd1 trial if there are any in Australia. I know Jim Stynes who being treated by my dad's oncologist is on this drug. From what I understand TIL requires you to be under the age of 60. I will ask the oncologist about this in 2 weeks. Thanks again.
Nahmi
-
- December 2, 2011 at 8:20 am
Ok thanks, I will do some research. Im keen to find out about Antipd1 trial if there are any in Australia. I know Jim Stynes who being treated by my dad's oncologist is on this drug. From what I understand TIL requires you to be under the age of 60. I will ask the oncologist about this in 2 weeks. Thanks again.
Nahmi
-
- December 2, 2011 at 7:16 am
Nahmi, I think that you will need to research the treatments for your dad. This will need a lot of work, but I think that it is necessary.
The Net makes it easier to find out where various treatments are available. However, you will also have to contact various treatment centres by phone and/or email to get more info.
You would also need to ring his oncologist to talk about this. A second opinion could also be an idea.
As you might know, I am also located in Melbourne. However, I don't know if that helps at all.
Take care
Frank from Australia
-
- December 2, 2011 at 7:16 am
Nahmi, I think that you will need to research the treatments for your dad. This will need a lot of work, but I think that it is necessary.
The Net makes it easier to find out where various treatments are available. However, you will also have to contact various treatment centres by phone and/or email to get more info.
You would also need to ring his oncologist to talk about this. A second opinion could also be an idea.
As you might know, I am also located in Melbourne. However, I don't know if that helps at all.
Take care
Frank from Australia
-
- December 1, 2011 at 3:29 am
Hi I am also interesting in answers on this topic. My dad is on Zelboraf month 3 and we feel like sitting ducks. The onocologist did mention that we could try MEK next, but I don't know why they didn't just give him the combination in the first place? What is next after Zelboraf or is that the last card?
Nahmi from Melbourne
-
- You must be logged in to reply to this topic.