Auto immune disease and immuno therapy

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  • Post
    • October 29, 2016 at 3:37 pm
    SOLE
    Participant

      Can the former prevent the latter?

    Viewing 8 reply threads
    • Replies
        • October 29, 2016 at 5:07 pm
        cancersnewnormal
        Participant
          • October 29, 2016 at 5:07 pm
          cancersnewnormal
          Participant
              • October 29, 2016 at 5:17 pm
              jpg
              Participant

                In fact it can cause the other,  immunotherapy can cause auto immune disease or make it worse.  there is a good discussion of it on http://www.melanomaforum.org, look for MarySue's posts.

                • October 29, 2016 at 5:17 pm
                jpg
                Participant

                  In fact it can cause the other,  immunotherapy can cause auto immune disease or make it worse.  there is a good discussion of it on http://www.melanomaforum.org, look for MarySue's posts.

                  • October 29, 2016 at 5:44 pm
                  cancersnewnormal
                  Participant

                    That is quite true. More and more immunotherapy patients are cropping up with autoimmune issues. My joints are currently screaming at me. From what I understand, patients with pre-existing autoimmune disease are not accepted into most of the current immunotherapy trials, however it does not exclude them from receiving currently approved drugs. That said, I would strongly recommend an oncologist specializing in melanoma if you are a patient with autoimmune issues.

                    • October 29, 2016 at 5:44 pm
                    cancersnewnormal
                    Participant

                      That is quite true. More and more immunotherapy patients are cropping up with autoimmune issues. My joints are currently screaming at me. From what I understand, patients with pre-existing autoimmune disease are not accepted into most of the current immunotherapy trials, however it does not exclude them from receiving currently approved drugs. That said, I would strongly recommend an oncologist specializing in melanoma if you are a patient with autoimmune issues.

                      • October 29, 2016 at 5:44 pm
                      cancersnewnormal
                      Participant

                        That is quite true. More and more immunotherapy patients are cropping up with autoimmune issues. My joints are currently screaming at me. From what I understand, patients with pre-existing autoimmune disease are not accepted into most of the current immunotherapy trials, however it does not exclude them from receiving currently approved drugs. That said, I would strongly recommend an oncologist specializing in melanoma if you are a patient with autoimmune issues.

                        • October 29, 2016 at 5:17 pm
                        jpg
                        Participant

                          In fact it can cause the other,  immunotherapy can cause auto immune disease or make it worse.  there is a good discussion of it on http://www.melanomaforum.org, look for MarySue's posts.

                        • October 29, 2016 at 5:07 pm
                        cancersnewnormal
                        Participant
                          • October 29, 2016 at 6:30 pm
                          Bubbles
                          Participant

                            Since we know that immunotherapy, of all sorts, can actually produce serious immune related side effects….for a long time folks with pre-existing immunologic disease were not allowed participation in trials, or were withheld from treatment, with those therapies.  Prior immune related disease is still a very important aspect to consider and should be carefully evaluated with an oncologist….ie not taken lightly….when considering immunotherapy as a treatment for melanoma.

                            However, we are learning that some patients with a pre-existing immuological disease process can achieve success with immunotherapy.

                            http://chaoticallypreciselifeloveandmelanoma.blogspot.com/2016/04/anti-pd1-success-in-melanoma-despite.html

                            c

                            • October 29, 2016 at 6:30 pm
                            Bubbles
                            Participant

                              Since we know that immunotherapy, of all sorts, can actually produce serious immune related side effects….for a long time folks with pre-existing immunologic disease were not allowed participation in trials, or were withheld from treatment, with those therapies.  Prior immune related disease is still a very important aspect to consider and should be carefully evaluated with an oncologist….ie not taken lightly….when considering immunotherapy as a treatment for melanoma.

                              However, we are learning that some patients with a pre-existing immuological disease process can achieve success with immunotherapy.

                              http://chaoticallypreciselifeloveandmelanoma.blogspot.com/2016/04/anti-pd1-success-in-melanoma-despite.html

                              c

                              • October 29, 2016 at 6:30 pm
                              Bubbles
                              Participant

                                Since we know that immunotherapy, of all sorts, can actually produce serious immune related side effects….for a long time folks with pre-existing immunologic disease were not allowed participation in trials, or were withheld from treatment, with those therapies.  Prior immune related disease is still a very important aspect to consider and should be carefully evaluated with an oncologist….ie not taken lightly….when considering immunotherapy as a treatment for melanoma.

                                However, we are learning that some patients with a pre-existing immuological disease process can achieve success with immunotherapy.

                                http://chaoticallypreciselifeloveandmelanoma.blogspot.com/2016/04/anti-pd1-success-in-melanoma-despite.html

                                c

                                • October 29, 2016 at 6:56 pm
                                SOLE
                                Participant

                                  Thank you for your answers. I ask because I have to find out about my agglutinate platelet condition that lowers my apparent count to 40,000-60,000. My oncologist was maybe thinking of a immune disease called ITP (i think…). I will be investigating this in the coming weeks. Needless to say, it is another source of stress knowing that cancer cells already aggreagate the platelets to form tumours

                                  • October 29, 2016 at 6:56 pm
                                  SOLE
                                  Participant

                                    Thank you for your answers. I ask because I have to find out about my agglutinate platelet condition that lowers my apparent count to 40,000-60,000. My oncologist was maybe thinking of a immune disease called ITP (i think…). I will be investigating this in the coming weeks. Needless to say, it is another source of stress knowing that cancer cells already aggreagate the platelets to form tumours

                                    • October 29, 2016 at 6:56 pm
                                    SOLE
                                    Participant

                                      Thank you for your answers. I ask because I have to find out about my agglutinate platelet condition that lowers my apparent count to 40,000-60,000. My oncologist was maybe thinking of a immune disease called ITP (i think…). I will be investigating this in the coming weeks. Needless to say, it is another source of stress knowing that cancer cells already aggreagate the platelets to form tumours

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