Peptides and Montanide ISA 51 VG with Escalating Doses of anti-PD-1 Antibody BMS-936558 for Patients with Unresectable Stages III/IV Melanoma….it was recommended to me but i still can;'t figure out my HLA type…i got test results back and can't make any sense out of it…anyway, please let me know if anyone on this board is on this study and how they are doing…thank you
post those results. Use a separate thread so you can put in the subject line 'need help with HLA test results. There are some folks here who are great with that stuff.
I don't know your study, though it sounds familiar…good luck!
post those results. Use a separate thread so you can put in the subject line 'need help with HLA test results. There are some folks here who are great with that stuff.
I don't know your study, though it sounds familiar…good luck!
I believe that lynnluckeroth@hotmail.com is on an AntiPD-1 trial (but not this exact one, I don't think) and is doing quite well (NED I think?). Perhaps you can contact her with some questions… : )
I believe that lynnluckeroth@hotmail.com is on an AntiPD-1 trial (but not this exact one, I don't think) and is doing quite well (NED I think?). Perhaps you can contact her with some questions… : )
Lynn is on the same trial but for those that are NED.She has a friend that is on that trial (at least I believe it's that one) who last I heard was doing well. E-mail Lynn and I'm sure she will be able to help.
Lynn is on the same trial but for those that are NED.She has a friend that is on that trial (at least I believe it's that one) who last I heard was doing well. E-mail Lynn and I'm sure she will be able to help.
Boots. Look up the 8/11 post from MariaH, on HLA testing, it was discussed in that post. Determining HLA typing is done by simple blood test and most vaccine trials like the one you are talking about require HLA02 positive. I think some people are doing this trial at moffiit. Good luck to you. Valerie (Phil’s wife)
Boots. Look up the 8/11 post from MariaH, on HLA testing, it was discussed in that post. Determining HLA typing is done by simple blood test and most vaccine trials like the one you are talking about require HLA02 positive. I think some people are doing this trial at moffiit. Good luck to you. Valerie (Phil’s wife)
Hi Boots! Just wanted to let you know that an ESO trial as well as the MAGE trial were both presented to Dave at NIH once he found out he was not eligible for the TIL study. We found out later he was HLA negative, but we did ask alot of questions regarding these while we were down in Bethesda. I know that they are having very positive results with them. I'm not sure if you would be doing this at NIH, and the procedure is different as NIH combined it with IL-2. If I were you, I would definitely look into this seriously. The science behind it makes sense, as technically you are blocking the cancer from growing and then teaching your immune system to recognize the tumors and attack. Sounds like a "win, win" situation in my book.
If you are HLA positive, it opens up a whole new scope on treatment options.
Good to see your posting, but I couldn't figure out what treatment you are doing now. My biochemo held things at bay, but didn't get rid of, or reduce, anything. CPMC wants me to go on Yervoy and then I called my original Onc at UCSF and he suggested an anti-PD1 trial they have. I had thought this was for Braf positive patients, which I am not. Now it seems that a bloodtest will tell me if I'm HLA positive is what I need to do. After reading about anti-PD1 I'd much rather go that route than IPI. I had enough side effects with the biochemo (neuropathy, rashes, nausea) to last a lifetime and IPI seems to have it's share.
Let me know what you're up to? Did you do biochemo? How are you doing? and, are you thinking about the anti-PD1 trials?
Good to see your posting, but I couldn't figure out what treatment you are doing now. My biochemo held things at bay, but didn't get rid of, or reduce, anything. CPMC wants me to go on Yervoy and then I called my original Onc at UCSF and he suggested an anti-PD1 trial they have. I had thought this was for Braf positive patients, which I am not. Now it seems that a bloodtest will tell me if I'm HLA positive is what I need to do. After reading about anti-PD1 I'd much rather go that route than IPI. I had enough side effects with the biochemo (neuropathy, rashes, nausea) to last a lifetime and IPI seems to have it's share.
Let me know what you're up to? Did you do biochemo? How are you doing? and, are you thinking about the anti-PD1 trials?
Hi Boots! Just wanted to let you know that an ESO trial as well as the MAGE trial were both presented to Dave at NIH once he found out he was not eligible for the TIL study. We found out later he was HLA negative, but we did ask alot of questions regarding these while we were down in Bethesda. I know that they are having very positive results with them. I'm not sure if you would be doing this at NIH, and the procedure is different as NIH combined it with IL-2. If I were you, I would definitely look into this seriously. The science behind it makes sense, as technically you are blocking the cancer from growing and then teaching your immune system to recognize the tumors and attack. Sounds like a "win, win" situation in my book.
If you are HLA positive, it opens up a whole new scope on treatment options.
Best wishes,
Maria
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