BRIM 8 or Vaccine Trial or Bio Chemo?

› Forums › General Melanoma Community › BRIM 8 or Vaccine Trial or Bio Chemo?

  • Post
    • December 9, 2014 at 7:00 pm
    spitfiregirl
    Participant

      hi everyone, first time joining the board, but have been reading your posts and gaining knowledge and strength!

      I'm a few weeks away from determining which clinical trial to participate in (or worse case – biochemo!). I will time out of these options around 1/8 or 1/9. I'm stage 3A resected (1 SLNB found, other 18 nodes clean – they thought it was .5mm but they went back and were able to find aggregate cells to bring it to the >1mm mark, which should allow me to participate in the BRIM study)

      It turns out I may qualify for the BRIM 8 clinical trial – I was wondering if anyone has participated in this, and what sorts of side effects I could expect. This is a placebo/drug trial (2 of 4 will receive drug).

      The vaccine Trial is placebo/drug trial, but 3 out of 4 will receive the drugs.

      Lastly, my (new to me) oncologist also suggested BioChemo – which I know is very toxic and intense. Has anyone done this and what were your results.

       

      Thank you so much for your help & support!

      ~h

       

       

    Viewing 2 reply threads
    • Replies
        • December 9, 2014 at 9:17 pm
        ed williams
        Participant

          Hi spitfiregirl, about the biochemo; there was a good talk about the topic on this forum, if you look back at older post maybe a month ago (ballpark). Wishing you the best of luck with your decision. Ed

          • December 9, 2014 at 9:17 pm
          ed williams
          Participant

            Hi spitfiregirl, about the biochemo; there was a good talk about the topic on this forum, if you look back at older post maybe a month ago (ballpark). Wishing you the best of luck with your decision. Ed

              • December 10, 2014 at 4:43 pm
              Cooper
              Participant

                Boy, none of these options look very promising.  Brim 8 is placebo blinded for Zelboraf.  Vaccines have not worked too well and biochemo proved no overall survival rate and definitely is overkill for 3A stage.  Watch and wait is your best bet in my humble opinion.  Stay strong!

                • December 10, 2014 at 4:43 pm
                Cooper
                Participant

                  Boy, none of these options look very promising.  Brim 8 is placebo blinded for Zelboraf.  Vaccines have not worked too well and biochemo proved no overall survival rate and definitely is overkill for 3A stage.  Watch and wait is your best bet in my humble opinion.  Stay strong!

                  • December 10, 2014 at 4:43 pm
                  Cooper
                  Participant

                    Boy, none of these options look very promising.  Brim 8 is placebo blinded for Zelboraf.  Vaccines have not worked too well and biochemo proved no overall survival rate and definitely is overkill for 3A stage.  Watch and wait is your best bet in my humble opinion.  Stay strong!

                    • December 10, 2014 at 6:22 pm
                    spitfiregirl
                    Participant

                      thanks ed! I can't seem to find that thread 🙁 I found too RIP posts that mention it but nothing further. If you happen to see it again and can send over, i'd greatly appreciate it!

                      • December 10, 2014 at 6:22 pm
                      spitfiregirl
                      Participant

                        thanks ed! I can't seem to find that thread 🙁 I found too RIP posts that mention it but nothing further. If you happen to see it again and can send over, i'd greatly appreciate it!

                        • December 10, 2014 at 6:22 pm
                        spitfiregirl
                        Participant

                          thanks ed! I can't seem to find that thread 🙁 I found too RIP posts that mention it but nothing further. If you happen to see it again and can send over, i'd greatly appreciate it!

                          • December 10, 2014 at 7:20 pm
                          ed williams
                          Participant

                            Hi spitfiregirl, I took a look at my old post and found it. It was a little farther back than I remembered, ( 9/30/2014, post is from Ronald Duclos.) Hope the post is of some help to you. Ed 

                            • December 10, 2014 at 7:20 pm
                            ed williams
                            Participant

                              Hi spitfiregirl, I took a look at my old post and found it. It was a little farther back than I remembered, ( 9/30/2014, post is from Ronald Duclos.) Hope the post is of some help to you. Ed 

                              • December 10, 2014 at 7:20 pm
                              ed williams
                              Participant

                                Hi spitfiregirl, I took a look at my old post and found it. It was a little farther back than I remembered, ( 9/30/2014, post is from Ronald Duclos.) Hope the post is of some help to you. Ed 

                              • December 9, 2014 at 9:17 pm
                              ed williams
                              Participant

                                Hi spitfiregirl, about the biochemo; there was a good talk about the topic on this forum, if you look back at older post maybe a month ago (ballpark). Wishing you the best of luck with your decision. Ed

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