Anybody on E7080, especially in Australia?

› Forums › General Melanoma Community › Anybody on E7080, especially in Australia?

  • Post
    • October 1, 2012 at 2:15 pm
    SharonAust
    Participant

      Hello from Sydney Australia,

      My friend has Stage IV unresectable melanoma (still confined to lymph). She has been on vemurafenib (Zelboraf) and had an unusually bad experience with side effects. She's been offered a place on trial of E7080, but is nervous to go on another clinical trial.

      Any info on side effects from E7080, especially compared to Zelboraf?

      Hello from Sydney Australia,

      My friend has Stage IV unresectable melanoma (still confined to lymph). She has been on vemurafenib (Zelboraf) and had an unusually bad experience with side effects. She's been offered a place on trial of E7080, but is nervous to go on another clinical trial.

      Any info on side effects from E7080, especially compared to Zelboraf?

    Viewing 5 reply threads
    • Replies
        • October 2, 2012 at 12:33 pm
        FormerCaregiver
        Participant

          Unfortunately, the big problem locally is that there is a serious lack stage IV
          treatment options. New clinical trials seem to be very limited in number, so it is good
          that your friend has the chance to try E7080. For more info see:
          http://www.nature.com/bjc/journal/v106/n10/full/bjc2012154a.html

          Hope this helps

          Frank from Australia

            • October 3, 2012 at 12:27 pm
            SharonAust
            Participant

              Hi Frank,

              Thanks for the info, much appreciated and best regards,

              Sharon

              • October 3, 2012 at 12:27 pm
              SharonAust
              Participant

                Hi Frank,

                Thanks for the info, much appreciated and best regards,

                Sharon

                • October 3, 2012 at 12:27 pm
                SharonAust
                Participant

                  Hi Frank,

                  Thanks for the info, much appreciated and best regards,

                  Sharon

                • October 2, 2012 at 12:33 pm
                FormerCaregiver
                Participant

                  Unfortunately, the big problem locally is that there is a serious lack stage IV
                  treatment options. New clinical trials seem to be very limited in number, so it is good
                  that your friend has the chance to try E7080. For more info see:
                  http://www.nature.com/bjc/journal/v106/n10/full/bjc2012154a.html

                  Hope this helps

                  Frank from Australia

                  • October 2, 2012 at 12:33 pm
                  FormerCaregiver
                  Participant

                    Unfortunately, the big problem locally is that there is a serious lack stage IV
                    treatment options. New clinical trials seem to be very limited in number, so it is good
                    that your friend has the chance to try E7080. For more info see:
                    http://www.nature.com/bjc/journal/v106/n10/full/bjc2012154a.html

                    Hope this helps

                    Frank from Australia

                    • October 2, 2012 at 2:34 pm
                    Lisa – Aust
                    Participant

                      Hi Sharon,

                      I am over in Perth and I know a few of the people who have stopped responding to the Braf inhibitor (GSK) have been offered the E7080 trial as the next option. A friend of ours, who was quite sick and has since passed, didnt have any major side effects at all. She actually stabilised on the drug (maybe some slight progression), but she was then taken off and given ipi, which she didnt have any luck with either, unfortunately. Another lady is still on the trial, but I havent seen her since she started, so unsure about her side effects.

                      I think I vaguely recall someone on the board having some luck with it, but I may be wrong.

                      Sorry to hear your friend had a hard time with Braf, and I hope she has some success with her next treatment.

                      Good luck

                      Lisa

                        • October 3, 2012 at 12:29 pm
                        SharonAust
                        Participant

                          Dear Lisa,

                          Thanks so much for the information and good wishes, much appreciated

                          Sharon

                          • October 3, 2012 at 12:29 pm
                          SharonAust
                          Participant

                            Dear Lisa,

                            Thanks so much for the information and good wishes, much appreciated

                            Sharon

                            • October 3, 2012 at 12:29 pm
                            SharonAust
                            Participant

                              Dear Lisa,

                              Thanks so much for the information and good wishes, much appreciated

                              Sharon

                            • October 2, 2012 at 2:34 pm
                            Lisa – Aust
                            Participant

                              Hi Sharon,

                              I am over in Perth and I know a few of the people who have stopped responding to the Braf inhibitor (GSK) have been offered the E7080 trial as the next option. A friend of ours, who was quite sick and has since passed, didnt have any major side effects at all. She actually stabilised on the drug (maybe some slight progression), but she was then taken off and given ipi, which she didnt have any luck with either, unfortunately. Another lady is still on the trial, but I havent seen her since she started, so unsure about her side effects.

                              I think I vaguely recall someone on the board having some luck with it, but I may be wrong.

                              Sorry to hear your friend had a hard time with Braf, and I hope she has some success with her next treatment.

                              Good luck

                              Lisa

                              • October 2, 2012 at 2:34 pm
                              Lisa – Aust
                              Participant

                                Hi Sharon,

                                I am over in Perth and I know a few of the people who have stopped responding to the Braf inhibitor (GSK) have been offered the E7080 trial as the next option. A friend of ours, who was quite sick and has since passed, didnt have any major side effects at all. She actually stabilised on the drug (maybe some slight progression), but she was then taken off and given ipi, which she didnt have any luck with either, unfortunately. Another lady is still on the trial, but I havent seen her since she started, so unsure about her side effects.

                                I think I vaguely recall someone on the board having some luck with it, but I may be wrong.

                                Sorry to hear your friend had a hard time with Braf, and I hope she has some success with her next treatment.

                                Good luck

                                Lisa

                            Viewing 5 reply threads
                            • You must be logged in to reply to this topic.
                            About the MRF Patient Forum

                            The MRF Patient Forum is the oldest and largest online community of people affected by melanoma. It is designed to provide peer support and information to caregivers, patients, family and friends. There is no better place to discuss different parts of your journey with this cancer and find the friends and support resources to make that journey more bearable.

                            The information on the forum is open and accessible to everyone. To add a new topic or to post a reply, you must be a registered user. Please note that you will be able to post both topics and replies anonymously even though you are logged in. All posts must abide by MRF posting policies.

                            Popular Topics