FYI an exciting trial It uses Anti PD 1 and ipi!

› Forums › General Melanoma Community › FYI an exciting trial It uses Anti PD 1 and ipi!

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      • July 2, 2011 at 1:49 pm
      LynnLuc
      Participant

        It's NOT Anti PD 1 LOL I need my glasses…still exciting tho

        • July 2, 2011 at 1:49 pm
        LynnLuc
        Participant

          It's NOT Anti PD 1 LOL I need my glasses…still exciting tho

            • July 2, 2011 at 1:55 pm
            nicoli
            Participant

              It's okay. Needing glasses just means we're getting OLD. And we who are fighting the beast LOVE TO GET OLD 🙂 I hope you live to be 100 !!

              Old and ALIVE, Nicki, Stage 3b

              • July 2, 2011 at 1:55 pm
              nicoli
              Participant

                It's okay. Needing glasses just means we're getting OLD. And we who are fighting the beast LOVE TO GET OLD 🙂 I hope you live to be 100 !!

                Old and ALIVE, Nicki, Stage 3b

                • July 2, 2011 at 6:45 pm
                LynnLuc
                Participant

                  You're right about Birthdays! It's the first time in my life I am happy to have birthdays and getting old!! It's truely a reason to celebrate!

                  • July 2, 2011 at 6:45 pm
                  LynnLuc
                  Participant

                    You're right about Birthdays! It's the first time in my life I am happy to have birthdays and getting old!! It's truely a reason to celebrate!

                    • July 2, 2011 at 6:46 pm
                    LynnLuc
                    Participant

                      You're right about Birthdays! It's the first time in my life I am happy to have birthdays and getting old!! It's truely a reason to celebrate!

                      • July 2, 2011 at 6:46 pm
                      LynnLuc
                      Participant

                        You're right about Birthdays! It's the first time in my life I am happy to have birthdays and getting old!! It's truely a reason to celebrate!

                        • July 2, 2011 at 6:47 pm
                        LynnLuc
                        Participant

                          It really is the first time in my life I can say I am happy to be getting old!! I don't like wearing glasses though!!

                          • July 2, 2011 at 6:47 pm
                          LynnLuc
                          Participant

                            It really is the first time in my life I can say I am happy to be getting old!! I don't like wearing glasses though!!

                            • July 2, 2011 at 1:58 pm
                            MariaH
                            Participant

                              Thanks for posting Lynn!  We are going to try and get Dave into one of these clinical trials – and I want him seen at UPMC also – they have a trial with IPI and GM-GSF. He sees the thoracic surgeon on Wednesday for post op check up – we'll have a boat load of questions for him then.

                              • July 2, 2011 at 1:58 pm
                              MariaH
                              Participant

                                Thanks for posting Lynn!  We are going to try and get Dave into one of these clinical trials – and I want him seen at UPMC also – they have a trial with IPI and GM-GSF. He sees the thoracic surgeon on Wednesday for post op check up – we'll have a boat load of questions for him then.

                                • July 2, 2011 at 4:42 pm
                                Cooper
                                Participant

                                  I think this is a trial for BRAF and IPI  NOT anti pd1 and IPI.sad

                                  • July 2, 2011 at 4:42 pm
                                  Cooper
                                  Participant

                                    I think this is a trial for BRAF and IPI  NOT anti pd1 and IPI.sad

                                    • July 2, 2011 at 6:44 pm
                                    LynnLuc
                                    Participant

                                      yep, you're right…I posted right afterwards…I put my glasses on!

                                      • July 2, 2011 at 6:44 pm
                                      LynnLuc
                                      Participant

                                        yep, you're right…I posted right afterwards…I put my glasses on!

                                      • July 3, 2011 at 4:47 am
                                      kylez
                                      Participant

                                        Hi Lynn,

                                        Here's a combo trial of MDX-1106 and IPI:

                                        http://clinicaltrials.gov/ct2/show/NCT01024231

                                        I started IPI (infusion #1) last week.

                                        – Kyle

                                        • July 3, 2011 at 4:47 am
                                        kylez
                                        Participant

                                          Hi Lynn,

                                          Here's a combo trial of MDX-1106 and IPI:

                                          http://clinicaltrials.gov/ct2/show/NCT01024231

                                          I started IPI (infusion #1) last week.

                                          – Kyle

                                            • July 3, 2011 at 4:52 am
                                            LynnLuc
                                            Participant

                                              I think this is the best trial to date!

                                              • July 3, 2011 at 4:52 am
                                              LynnLuc
                                              Participant

                                                I think this is the best trial to date!

                                                • July 4, 2011 at 1:34 pm
                                                nickmac56
                                                Participant

                                                  does anyone know what this exclusion for this trial means?  On the surface that would say you need to be NED or stable – but hard to believe it would be that restrictive.

                                                   

                                                  Prior malignancy active within the previous 2 years

                                                  • July 4, 2011 at 4:06 pm
                                                  kylez
                                                  Participant

                                                    with an inclusion criteria of "Measurable unresectable Stage III or IV MEL", I believe an exclusion criteria of "Prior malignancy active within the previous 2 years" usually means if there was another cancer other than melanoma.

                                                    For example, a more explicitly worded exclusion criteria I've seen is "Prior malignancy within the preceding five years, with the exception of non-melanoma skin cancers."

                                                    • July 4, 2011 at 4:06 pm
                                                    kylez
                                                    Participant

                                                      with an inclusion criteria of "Measurable unresectable Stage III or IV MEL", I believe an exclusion criteria of "Prior malignancy active within the previous 2 years" usually means if there was another cancer other than melanoma.

                                                      For example, a more explicitly worded exclusion criteria I've seen is "Prior malignancy within the preceding five years, with the exception of non-melanoma skin cancers."

                                                      • July 4, 2011 at 1:34 pm
                                                      nickmac56
                                                      Participant

                                                        does anyone know what this exclusion for this trial means?  On the surface that would say you need to be NED or stable – but hard to believe it would be that restrictive.

                                                         

                                                        Prior malignancy active within the previous 2 years

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