Hubby is BRAF positive, yay!

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  • Post
    • May 27, 2011 at 2:00 am
    shellebrownies
    Participant

      We got word yesterday that Don tested positive for the BRAF mutation. The nurse called us right away and we went right in to Boston to get him signed up for the GSK BRAF/MEK trial. In the interest of expediency (and to help get his pain level under control…he'd been having some issues with that this week), Dr. Lawrence put him in the hospital to get his trial pretests done quickly. He told us he didn't think he'd have any problems passing them, but I am still waiting on baited breath for when they tell us he's officially in!

       

      We got word yesterday that Don tested positive for the BRAF mutation. The nurse called us right away and we went right in to Boston to get him signed up for the GSK BRAF/MEK trial. In the interest of expediency (and to help get his pain level under control…he'd been having some issues with that this week), Dr. Lawrence put him in the hospital to get his trial pretests done quickly. He told us he didn't think he'd have any problems passing them, but I am still waiting on baited breath for when they tell us he's officially in!

       

      Michelle, wife of Don, Stage IV

    Viewing 11 reply threads
    • Replies
        • May 27, 2011 at 2:07 am
        NicOz
        Participant

          Great to hear Michelle, and waiting for the pre-screening results leaves on holding their breath, doesn't it? I'll be looking forward to hearing he has a start date, soon!

          Nic 🙂

          • May 27, 2011 at 2:07 am
          NicOz
          Participant

            Great to hear Michelle, and waiting for the pre-screening results leaves on holding their breath, doesn't it? I'll be looking forward to hearing he has a start date, soon!

            Nic 🙂

            • May 27, 2011 at 2:10 am
            Carol Taylor
            Participant

              Great start Michelle! You're jumping the hurdles! Prayers for continued positive news.

              Lord, in Your mercy, make a way for Don! Amen.

              Grace and peace,

              Carol

              • May 27, 2011 at 2:10 am
              Carol Taylor
              Participant

                Great start Michelle! You're jumping the hurdles! Prayers for continued positive news.

                Lord, in Your mercy, make a way for Don! Amen.

                Grace and peace,

                Carol

                • May 27, 2011 at 3:48 am
                jag
                Participant

                  Michelle, I will say a prayer for you and your husband that he gets in and treatment is successful.

                  Do you know the trial name/number?

                  John

                    • May 27, 2011 at 10:41 am
                    shellebrownies
                    Participant

                      His trial's official name has a ridiculously long name: 

                      An Open-Label, Dose-Escalation, Phase I Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of the BRAF Inhibitor GSK2118436 in Combination With the MEK Inhibitor GSK1120212 in Subjects With BRAF Mutant Metastatic Melanoma
                       

                      Link to it on Clinical Trials dot Gov: http://clinicaltrials.gov/ct2/show/NCT01072175?term=melanoma+boston&recr=Open&rank=11

                      Michelle

                      • May 27, 2011 at 10:55 am
                      dawn dion
                      Participant

                        I and a few others here are on this trial – so far so good.  Lots of great results.  I go to Moffitt in Tampa and they can't quit singing it's praises.  

                        The response is pretty quick – don't be surprised if he starts busting a fever that can get pretty wacky and last on and off for a while – it is quite the norm.   Post if you have any questions and welcome to the train.   I hope it does wonderful things for him.

                        • May 27, 2011 at 10:55 am
                        dawn dion
                        Participant

                          I and a few others here are on this trial – so far so good.  Lots of great results.  I go to Moffitt in Tampa and they can't quit singing it's praises.  

                          The response is pretty quick – don't be surprised if he starts busting a fever that can get pretty wacky and last on and off for a while – it is quite the norm.   Post if you have any questions and welcome to the train.   I hope it does wonderful things for him.

                          • May 27, 2011 at 10:41 am
                          shellebrownies
                          Participant

                            His trial's official name has a ridiculously long name: 

                            An Open-Label, Dose-Escalation, Phase I Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of the BRAF Inhibitor GSK2118436 in Combination With the MEK Inhibitor GSK1120212 in Subjects With BRAF Mutant Metastatic Melanoma
                             

                            Link to it on Clinical Trials dot Gov: http://clinicaltrials.gov/ct2/show/NCT01072175?term=melanoma+boston&recr=Open&rank=11

                            Michelle

                          • May 27, 2011 at 3:48 am
                          jag
                          Participant

                            Michelle, I will say a prayer for you and your husband that he gets in and treatment is successful.

                            Do you know the trial name/number?

                            John

                            • May 27, 2011 at 11:12 am
                            MichaelFL
                            Participant

                              Glad he is positive! (sounds weird right?)

                              Give yourselves some time to catch your breath and then plan ahead with your next course of action-should you need it.

                              Good luck,

                              Michael

                              • May 27, 2011 at 11:12 am
                              MichaelFL
                              Participant

                                Glad he is positive! (sounds weird right?)

                                Give yourselves some time to catch your breath and then plan ahead with your next course of action-should you need it.

                                Good luck,

                                Michael

                                • May 28, 2011 at 11:36 pm
                                debandmike
                                Participant

                                  What wonderful news, Michelle. I will hope and pray that your husband's treatment gives you positive results. I'm sure that you feel such a sense of releif that there is something out there to fight the cancer, but at the same time feeling anxious. Keep the faith.

                                  • May 28, 2011 at 11:36 pm
                                  debandmike
                                  Participant

                                    What wonderful news, Michelle. I will hope and pray that your husband's treatment gives you positive results. I'm sure that you feel such a sense of releif that there is something out there to fight the cancer, but at the same time feeling anxious. Keep the faith.

                                    • May 28, 2011 at 11:36 pm
                                    debandmike
                                    Participant

                                      What wonderful news, Michelle. I will hope and pray that your husband's treatment gives you positive results. I'm sure that you feel such a sense of releif that there is something out there to fight the cancer, but at the same time feeling anxious. Keep the faith.

                                      • May 28, 2011 at 11:36 pm
                                      debandmike
                                      Participant

                                        What wonderful news, Michelle. I will hope and pray that your husband's treatment gives you positive results. I'm sure that you feel such a sense of releif that there is something out there to fight the cancer, but at the same time feeling anxious. Keep the faith.

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