Anti-LAG-3 Trial Post-Infusion 3 Report

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    • July 22, 2017 at 2:46 am
    mrsaxde
    Participant

      Hello! I had my third infusion in the trial last Tuesday. I don't have much to report. Still not experiencing anything in the way of side effects, other than some occasional mild fatigue and a very mild rash on my upper chest.

      I haven't had the chance to ask a question about this yet, but I have noticed that in my blood work my lymphocyte count has been increasing fairly significantly. It was below normal when I started the trial, and it has now returned to the normal range. On 5/30 the lymphocyte values were 1.18/14.8%. On 7/5, before my second infusion, they had increased to 1.44/16.4%. And on 7/18 they had increased again to 1.55/24.3%

      The anti-LAG-3 antibody is supposed to help invigorate exhausted t-cells, and I can't help but wonder whether those lymphocyte values might indicate that it is starting to do its job. If anybody on this board has any insight, I'd love to hear you weigh in.

      So my next infusion comes on August 1, and my scans at the end of the first 45 day cycle come on August 11. I'll be back with another update after I get the scan results, unless something significant happens in the meantime.

      I hope everybody has a pleasant weekend!

      -Bill

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        • July 23, 2017 at 11:46 am
        BrianP
        Participant

          Thanks for the update Bill.  Hope that blood work is a good sign for your scans.  It sounds promising to me.

          Brian

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