Hello Everybody,
I had my second infusion in the anti-LAG3 trial at Johns Hopkins on Wednesday. I don't really have anything to report. I seem to be tolerating the combination of the experimental treatment and Opdivo very well, with no noticeable side effects so far. My blood work is all good and the only side effect we have seen appears to be a very mild rash on my upper chest and back.
Another patient was apparently not so lucky with her treatment. During my first treatment the research nurse mentioned that another patient who was also starting the trial was experiencing a range of side effects. On Wednesday there was a woman behind me who my wife believed was probably the patient who had had problems last time. I wasn't paying much attention because my back was to her, but my wife was facing in that direction, and she said the woman never made it to the experimental medication. They give you an infusion of Opdivo first, then the new drug after a 30 minute break. Apparently this woman had an allergic reaction to the Opdivo, which they were fortunately able to quickly control.
My next infusion is on the 18th. The first scans come on August 11. If anything changes I'll update. Otherwise I'll have another report after the 18th.
-Bill
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