Starting Anti-LAG-3 Trial At Johns Hopkins

› Forums › General Melanoma Community › Starting Anti-LAG-3 Trial At Johns Hopkins

  • Post
    • May 31, 2017 at 7:21 pm
    mrsaxde
    Participant

      Hi Everyone,

      I went to Johns Hopkins yesterday for the screening process, and everything looks good for me to start in the anti-LAG-3/nivolumab trial. Dr. Sharfman thinks I'll have a better outcome with the trial than I would have with the treatment my local oncologist had planned — radiation followed by more Keytruda. Apparently there have been a few melanoma patients in the trial who have gotten good results from the combo of the experimental drug and nivo. So I'm really feeling hopeful. The plan is to get the first infusion week after next.

      Unfortunately it looks like I'll have to undergo another lung procedure prior to starting, though. BMS, the sponsor of the trial, wants a "fresh" biopsy prior to starting. The only things that are positive on me right now are my hilar and subcarinal lymph nodes, which were confirmed by a fine needle aspiration on April 6. But that procedure apparently isn't fresh enough, so it looks like another trip under general anesthesia for me. Still, you do what you gotta do, n'est pas?

      I'll keep everybody updated as I go through this. If anybody else here is on or planning to go on this trial, please let me know. I'd like to share and compare notes with you.

      -Bill

    Viewing 1 reply thread
    • Replies
        • May 31, 2017 at 7:26 pm
        Mat
        Participant

          Bill, sounds like a good plan.  Good luck.

          • May 31, 2017 at 11:09 pm
          Bubbles
          Participant

            Reports on combo's with LAG-3 are very promising, Bill!  Hope your procedure goes as easily as possible and you get excellent results from this trial!!! yours, c

        Viewing 1 reply thread
        • You must be logged in to reply to this topic.
        About the MRF Patient Forum

        The MRF Patient Forum is the oldest and largest online community of people affected by melanoma. It is designed to provide peer support and information to caregivers, patients, family and friends. There is no better place to discuss different parts of your journey with this cancer and find the friends and support resources to make that journey more bearable.

        The information on the forum is open and accessible to everyone. To add a new topic or to post a reply, you must be a registered user. Please note that you will be able to post both topics and replies anonymously even though you are logged in. All posts must abide by MRF posting policies.

        Popular Topics