Gamma Knife is the best treatment for Melanoma brain mets if compared with other SRS methods and WBRT.
My husband had a craniotomy in October to remove 1 large lesion – 2.5 cm and in three weeks he had his first Gamma Knife procedure to treat 10 remaining lesion – sizes from 1mm to 2 cm.
the subsequent MRI in 8 weeks showed very promising results – all of them shrunk by 30-40 %%.
since November he was on the Taff/Mek combo, but had to stop in late January because of adverse reaction – very high fever (103-104) and terrible chills – almost every week.
we started on PD-1 – Keytruda in February.
the next MRI in February showed new growth so we had our second Gamma Knife treatment this week. The MRI performed before the procedure revealed 20! New leasions – sized from 1mm to 10mm. They all were treated.
although radiologist suggested that in case progression will not stop he recommends WBRT next time.
We are trying to avoid it. So will continue with Keytruda and wait for the next MRI in 6 weeks.
Our position is to stick with PD-1 and Gamma Knife for as long as possible. Unless another craniotomy will be required
–Zina
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