KEYTRUDA

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  • Post
    • January 28, 2017 at 5:51 pm
    TommyD
    Participant

      Greetings all

      Im new to the forum as a newly diagnosed stage 4 melanoma patient. My oncologist has recommended the immunology therapy using the drug Keytruda (Pembrolizumab).  Wondering if anyone has any experience with this treatment and it's side effects. 

      Thanks

      TommyD

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    • Replies
        • January 28, 2017 at 6:33 pm
        Bubbles
        Participant

          Hi Tommy, 

          You can use the search option on this forum to find many stories about Keytruda specifically and anti-PD1 generally.  Keytruda (Pembrolizumab) and Opdivo (Nivolizumab) are both anti-PD1 products with similar response rates (about 40%) and side effect profiles.  I put this together some time ago…but perhaps you will find it helpful:

          http://chaoticallypreciselifeloveandmelanoma.blogspot.com/2014/04/background-and-latest-info-on-anti-pd1.html

          I wish you well.  Celeste

          • January 28, 2017 at 6:33 pm
          Bubbles
          Participant

            Hi Tommy, 

            You can use the search option on this forum to find many stories about Keytruda specifically and anti-PD1 generally.  Keytruda (Pembrolizumab) and Opdivo (Nivolizumab) are both anti-PD1 products with similar response rates (about 40%) and side effect profiles.  I put this together some time ago…but perhaps you will find it helpful:

            http://chaoticallypreciselifeloveandmelanoma.blogspot.com/2014/04/background-and-latest-info-on-anti-pd1.html

            I wish you well.  Celeste

              • January 29, 2017 at 2:41 pm
              aingeal
              Participant

                Hi Tommy: Keytruda is a very effective treatment for advanced melanoma, My 86 year old mother was treated for stage iv melanoma with mets to her abdomen with Keytruda after all hope was thought to be lost. It wasn't, the Keytruda shrank her tumors by more than 75%, and some are hardly detectable anymore on the CT/PET scan. Her side effects included skin rash, and colitiis controlled with prednisone, and immodium and diet for the diarrhea. My understanding is Keytruda has much less sisde effects than Opdivo. She feels 100% better now after treatment than she did before. I wish you success with your treatment, and I think Keytruda is truly and revolutionary immunotherapy for advanced melanoma, and other cancer patients. 

                • January 29, 2017 at 2:41 pm
                aingeal
                Participant

                  Hi Tommy: Keytruda is a very effective treatment for advanced melanoma, My 86 year old mother was treated for stage iv melanoma with mets to her abdomen with Keytruda after all hope was thought to be lost. It wasn't, the Keytruda shrank her tumors by more than 75%, and some are hardly detectable anymore on the CT/PET scan. Her side effects included skin rash, and colitiis controlled with prednisone, and immodium and diet for the diarrhea. My understanding is Keytruda has much less sisde effects than Opdivo. She feels 100% better now after treatment than she did before. I wish you success with your treatment, and I think Keytruda is truly and revolutionary immunotherapy for advanced melanoma, and other cancer patients. 

                  • January 29, 2017 at 2:41 pm
                  aingeal
                  Participant

                    Hi Tommy: Keytruda is a very effective treatment for advanced melanoma, My 86 year old mother was treated for stage iv melanoma with mets to her abdomen with Keytruda after all hope was thought to be lost. It wasn't, the Keytruda shrank her tumors by more than 75%, and some are hardly detectable anymore on the CT/PET scan. Her side effects included skin rash, and colitiis controlled with prednisone, and immodium and diet for the diarrhea. My understanding is Keytruda has much less sisde effects than Opdivo. She feels 100% better now after treatment than she did before. I wish you success with your treatment, and I think Keytruda is truly and revolutionary immunotherapy for advanced melanoma, and other cancer patients. 

                  • January 28, 2017 at 6:33 pm
                  Bubbles
                  Participant

                    Hi Tommy, 

                    You can use the search option on this forum to find many stories about Keytruda specifically and anti-PD1 generally.  Keytruda (Pembrolizumab) and Opdivo (Nivolizumab) are both anti-PD1 products with similar response rates (about 40%) and side effect profiles.  I put this together some time ago…but perhaps you will find it helpful:

                    http://chaoticallypreciselifeloveandmelanoma.blogspot.com/2014/04/background-and-latest-info-on-anti-pd1.html

                    I wish you well.  Celeste

                    • January 29, 2017 at 9:55 pm
                    stevenallenschwartz
                    Participant

                      I have had 2 infusions so far and am scheduled for my 3rd infusion tomorrow. Besides being a bit tired 2 days after the infusion I have had no serious side effects. Good luck….

                      • January 29, 2017 at 9:55 pm
                      stevenallenschwartz
                      Participant

                        I have had 2 infusions so far and am scheduled for my 3rd infusion tomorrow. Besides being a bit tired 2 days after the infusion I have had no serious side effects. Good luck….

                        • January 29, 2017 at 9:55 pm
                        stevenallenschwartz
                        Participant

                          I have had 2 infusions so far and am scheduled for my 3rd infusion tomorrow. Besides being a bit tired 2 days after the infusion I have had no serious side effects. Good luck….

                          • January 29, 2017 at 10:20 pm
                          Nick C
                          Participant

                            I had two infusions and have not noticed any changes so far. Hope everything goes well for you.

                            Nick

                            • January 29, 2017 at 10:20 pm
                            Nick C
                            Participant

                              I had two infusions and have not noticed any changes so far. Hope everything goes well for you.

                              Nick

                              • January 29, 2017 at 10:20 pm
                              Nick C
                              Participant

                                I had two infusions and have not noticed any changes so far. Hope everything goes well for you.

                                Nick

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