Targeted Therapy

This topic has 24 replies, 4 voices, and was last updated 9 years, 2 months ago by Cindyco.

Post

- January 13, 2017 at 11:33 pm
- Quote
Cindyco
Participant
Hi Everyone,

Has anyone participated in or have any thoughts on the tumor testing trials for targeted therapy? There are a couple that I was looking into for my mom, but I haven't heard of many patients on the board going this route. Would love to learn more about it so that I can schedule a consultation for one or the other.

NCI-MATCH:

https://clinicaltrials.gov/ct2/show/NCT02465060?term=nci+match&rank=1

I-PREDICT:

https://clinicaltrials.gov/ct2/show/NCT02534675

Viewing 5 reply threads

Replies

- - January 14, 2017 at 4:23 am
  - Quote
  snow white
  Participant
  I haven't heard of this. Hopefully Celeste and Ed can chime in and let you know if they have.
- - January 14, 2017 at 4:23 am
  - Quote
  snow white
  Participant
  I haven't heard of this. Hopefully Celeste and Ed can chime in and let you know if they have.
- - January 14, 2017 at 4:23 am
  - Quote
  snow white
  Participant
  I haven't heard of this. Hopefully Celeste and Ed can chime in and let you know if they have.
- - January 14, 2017 at 5:40 am
  - Quote
  debwray
  Participant
  Hi Cindy,
  
  How did the radiation go ? Or is your Mum still waiting ?
  
  No experience but have read about this kind of personalised medicine where the tumours DNA is tested and bench tested against a known panel of anti cancer drugs and then the patient is given the one that looks the most promising. Sounds expensive to do and unlikely to be funded by big pharma but if I rember correctly some melanomas responded to one of the breast cancer drugs.Think it was a Her2 drug in that case from memory. Will have a browse and see if I can find details or anything else about that might be useful.
  
  Best wishes
  
  Deb
  - January 14, 2017 at 6:03 am
    
    Quote
    debwray
    Participant
    
    Article in Nature 31/7/2015 NCI-match trial pushes cancer umbrella trial paradigim. Should come high in search if you push title into google. Not good with links on tablet…
  - January 14, 2017 at 3:02 pm
    
    Quote
    debwray
    Participant
    
    link http://www.nature.com/articles/nrd4694.epdf?referrer_access_token=6sRmc4DCjCQQsxn1U6ZBhNRgN0jAjWel9jnR3ZoTv0OGlWgadLDx1z_aTG4o2NqgqJ1pTzjdrOewRplhd8jQ4Yoc5x_unasswqB_FmjpnTUmxU9rlxp1Rr6vdsIw0Yu4Vij1PKnp9CHxS51OFMQBWWKna0DYi7ss0YZHC2ZXRumoYuIlSWWCNxw0UdZW3-Keaht_gGR1_VOCt3_dOlP2FJSXPOFKYfV6NbYf0BdOzIj38SYQw_TaOEwYF5wuUiK1N2yTUxUdxS7HkFtdAMKzGQ%3D%3D&tracking_referrer=www.nature.com
  - January 14, 2017 at 3:02 pm
    
    Quote
    debwray
    Participant
    
    link http://www.nature.com/articles/nrd4694.epdf?referrer_access_token=6sRmc4DCjCQQsxn1U6ZBhNRgN0jAjWel9jnR3ZoTv0OGlWgadLDx1z_aTG4o2NqgqJ1pTzjdrOewRplhd8jQ4Yoc5x_unasswqB_FmjpnTUmxU9rlxp1Rr6vdsIw0Yu4Vij1PKnp9CHxS51OFMQBWWKna0DYi7ss0YZHC2ZXRumoYuIlSWWCNxw0UdZW3-Keaht_gGR1_VOCt3_dOlP2FJSXPOFKYfV6NbYf0BdOzIj38SYQw_TaOEwYF5wuUiK1N2yTUxUdxS7HkFtdAMKzGQ%3D%3D&tracking_referrer=www.nature.com
  - January 14, 2017 at 4:30 pm
    
    Quote
    ed williams
    Participant
    
    Hi Cindy, Deb and Jennifer, I have read a few articles about the NCI-Match trial and my first thought on this one is talk with your Oncologist on this topic. We tend to give the advice often to new members, to see a Melanoma specialist. I am not sure if the experts in the Melanoma field are on board on this program, maybe a great question to ask Dr. Omid Hamid about Jennifer!!! Best Wishes!!!Ed
  - January 14, 2017 at 4:30 pm
    
    Quote
    ed williams
    Participant
    
    Hi Cindy, Deb and Jennifer, I have read a few articles about the NCI-Match trial and my first thought on this one is talk with your Oncologist on this topic. We tend to give the advice often to new members, to see a Melanoma specialist. I am not sure if the experts in the Melanoma field are on board on this program, maybe a great question to ask Dr. Omid Hamid about Jennifer!!! Best Wishes!!!Ed
  - January 15, 2017 at 7:37 pm
    
    Quote
    snow white
    Participant
    
    will do Ed!
  - January 16, 2017 at 6:00 am
    
    Quote
    Cindyco
    Participant
    
    Thanks Ed!
    
    Jen, if you find out more from Dr. Hamid, please do share!
  - January 16, 2017 at 6:00 am
    
    Quote
    Cindyco
    Participant
    
    Thanks Ed!
    
    Jen, if you find out more from Dr. Hamid, please do share!
  - January 16, 2017 at 6:00 am
    
    Quote
    Cindyco
    Participant
    
    Thanks Ed!
    
    Jen, if you find out more from Dr. Hamid, please do share!
  - January 15, 2017 at 7:37 pm
    
    Quote
    snow white
    Participant
    
    will do Ed!
  - January 15, 2017 at 7:37 pm
    
    Quote
    snow white
    Participant
    
    will do Ed!
  - January 14, 2017 at 4:30 pm
    
    Quote
    ed williams
    Participant
    
    Hi Cindy, Deb and Jennifer, I have read a few articles about the NCI-Match trial and my first thought on this one is talk with your Oncologist on this topic. We tend to give the advice often to new members, to see a Melanoma specialist. I am not sure if the experts in the Melanoma field are on board on this program, maybe a great question to ask Dr. Omid Hamid about Jennifer!!! Best Wishes!!!Ed
  - January 14, 2017 at 3:02 pm
    
    Quote
    debwray
    Participant
    
    link http://www.nature.com/articles/nrd4694.epdf?referrer_access_token=6sRmc4DCjCQQsxn1U6ZBhNRgN0jAjWel9jnR3ZoTv0OGlWgadLDx1z_aTG4o2NqgqJ1pTzjdrOewRplhd8jQ4Yoc5x_unasswqB_FmjpnTUmxU9rlxp1Rr6vdsIw0Yu4Vij1PKnp9CHxS51OFMQBWWKna0DYi7ss0YZHC2ZXRumoYuIlSWWCNxw0UdZW3-Keaht_gGR1_VOCt3_dOlP2FJSXPOFKYfV6NbYf0BdOzIj38SYQw_TaOEwYF5wuUiK1N2yTUxUdxS7HkFtdAMKzGQ%3D%3D&tracking_referrer=www.nature.com
  - January 14, 2017 at 6:03 am
    
    Quote
    debwray
    Participant
    
    Article in Nature 31/7/2015 NCI-match trial pushes cancer umbrella trial paradigim. Should come high in search if you push title into google. Not good with links on tablet…
  - January 14, 2017 at 6:03 am
    
    Quote
    debwray
    Participant
    
    Article in Nature 31/7/2015 NCI-match trial pushes cancer umbrella trial paradigim. Should come high in search if you push title into google. Not good with links on tablet…
  - January 16, 2017 at 5:59 am
    
    Quote
    Cindyco
    Participant
    
    Hi Deb,
    
    Thanks for asking. Radiation is on Tuesday, so we're anxiously waiting to start. We also have an appointment with her oncologist on Wednesday so I'm going to ask about the targeted therapy trial. I think this is still an early trial, so I'm not sure if there is a lot of information on it yet, but I will post updates if I find out more!
  - January 16, 2017 at 5:59 am
    
    Quote
    Cindyco
    Participant
    
    Hi Deb,
    
    Thanks for asking. Radiation is on Tuesday, so we're anxiously waiting to start. We also have an appointment with her oncologist on Wednesday so I'm going to ask about the targeted therapy trial. I think this is still an early trial, so I'm not sure if there is a lot of information on it yet, but I will post updates if I find out more!
  - January 16, 2017 at 5:59 am
    
    Quote
    Cindyco
    Participant
    
    Hi Deb,
    
    Thanks for asking. Radiation is on Tuesday, so we're anxiously waiting to start. We also have an appointment with her oncologist on Wednesday so I'm going to ask about the targeted therapy trial. I think this is still an early trial, so I'm not sure if there is a lot of information on it yet, but I will post updates if I find out more!
- - January 14, 2017 at 5:40 am
  - Quote
  debwray
  Participant
  Hi Cindy,
  
  How did the radiation go ? Or is your Mum still waiting ?
  
  No experience but have read about this kind of personalised medicine where the tumours DNA is tested and bench tested against a known panel of anti cancer drugs and then the patient is given the one that looks the most promising. Sounds expensive to do and unlikely to be funded by big pharma but if I rember correctly some melanomas responded to one of the breast cancer drugs.Think it was a Her2 drug in that case from memory. Will have a browse and see if I can find details or anything else about that might be useful.
  
  Best wishes
  
  Deb
- - January 14, 2017 at 5:40 am
  - Quote
  debwray
  Participant
  Hi Cindy,
  
  How did the radiation go ? Or is your Mum still waiting ?
  
  No experience but have read about this kind of personalised medicine where the tumours DNA is tested and bench tested against a known panel of anti cancer drugs and then the patient is given the one that looks the most promising. Sounds expensive to do and unlikely to be funded by big pharma but if I rember correctly some melanomas responded to one of the breast cancer drugs.Think it was a Her2 drug in that case from memory. Will have a browse and see if I can find details or anything else about that might be useful.
  
  Best wishes
  
  Deb

Viewing 5 reply threads

You must be logged in to reply to this topic.

About the MRF Patient Forum

Popular Topics

Targeted Therapy

About the MRF Patient Forum

Popular Topics

Topic Tags