New molecule DEL-22379 unaffected by resistance that hamper BRAF/MEK inhibitors

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    • August 18, 2015 at 8:58 am
    bjorne
    Participant

      I found this Cell article, I found it very interesting and I would like to share it with you all, maybe someone with more knowledge,  or contacts with MD doctors or researches could give a read.

      http://www.cell.com/cancer-cell/abstract/S1535-6108(15)00253-6

      it sounds promising as it follows a new (at least for me) concept of treatment.  I hope that someone can put this in MD o Researchers hands. 

      "The strategy is decoupling molecular interactions in a key point in the chain of transmission.  This is what achieves the DEL-22379 molecule that prevents teh association (dimerization) between two proteins ERK. 

      Thank you all

      Husband

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